Dr. Li Zhao received her PhD from Baylor College of Medicine and is currently working as a computational scientist in the University of Texas MD Anderson Cancer Center. She is a member of ASHG (the American Society of Human Genetics) and ARVO (the Association for Research in Vision and Ophthalmology). Her research focused on understanding the molecular mechanisms underlying inherited retinal diseases from both computational and experimental approaches. Dr. Zhao has been working on identifying causative genes involved in several human retinal diseases such as Retinitis pigmentosa, Leber congenital amaurosis and Cone-rod dystrophy etc. Over the past six years, Dr. Zhao together with her collaborators have successfully identified over 10 novel retinal disease genes by applying the next-generation sequencing technologies coupled with functional analysis to the patient samples. In addition, she developed novel methodology which integrated subcellular proteomics and transcriptomics to predict the retinal disease genes and identify genetic networks controlling retinal development. She is also an expert in biostatistics, bioinformatics and cancer genomics. She has published more than 20 peer-reviewed papers and served as a reviewer for many reputed journals.
Inherited retinal disease, next-generation sequencing, molecular diagnosis, novel retinal disease gene discovery.