Biography

Sandri Giuseppina was born in 1975 and she is married with three sons. She obtained the Degree in Chemistry and Pharmaceutical Technology cum laude in 1999 and the PhD in Chemistry and Pharmaceutical Technology in 2003. She took post graduate Master Degree in “Pharmaceutical Technology and Regulatory Activity” in 2004 and post graduate Master Degree in “Preformulation and Galenic Development” in 2007. She was assistant professor from 2008 to 2015 and Associate Professor of Pharmaceutical Technology since 2015 at Drug Science Department (Faculty of Pharmacy) at University of Pavia. Her teaching activities are in undergraduate course in Pharmacy and Pharmaceutical Chemistry and Technology) and in post-graduate Master and PhD courses. She is Member of board of teachers of Ph.D. on “Drug, Biomolecule and Health Product Sciences” Univ. Parma, Member of board of teachers of Master Course on “Preformulation, Pharmaceutical Development and Control of Medicines” Dept. Drug Sciences, Univ Pavia. Her research interests concern pharmaceutical development of conventional and controlled release therapeutic systems. Early research works focused on the characterization of polymers, as mucoadhesive and penetration enhancement materials via (trans)mucosal routes other than oral one and in particular via buccal and vaginal routes. A part of the research work served the purpose to clarify the penetration enhancement mechanism of chitosan toward buccal mucosa. In parallel the ocular route was also studied in order to enhance the bioavailability of drugs poorly permeable across the cornea. The experience gained on these materials and their properties allowed the development of solid/semisolid (matrix tablets, films, gels, thermosentive systems) and nanoparticulate systems (nanoparticles, micelles and solid lipid nanoparticles). Nanoparticulate formulations were also developed to deliver proteins (in particular insulin) via oral route. Ad hoc tests (in vitro, cell cultures, and ex vivo, excised mucosae) were also developed to evaluate mucoadhesion and penetration enhancement. Current research concerns the development of semisolid and solid (sponge-like dressings, scaffolds, particulate systems) formulations for the treatment of mucosal, corneal and skin lesions. Attention was focused on the choice and the characterization of bioactive polymers (alginates, chitosan, chondroitin sulfate and hyaluronic acid) to be combined with hemoderivatives (such as platelet lysate, rich in growth factors) and eventually antimicrobials to promote wound healing. In this area of interest, medical devices and antimicrobial based formulations based on electrospun nanofibers are currently in study for heath regeneration. Her scientific and research activities were awarded with Actimex Awards (2002), Best poster award, 45° Simposium AFI (2005), Travel Grant CRS 33th Annual Meeting and Exhibition (2006), Most cited paper 2004 Award Elsevier (2007), Best poster award, 4th AItUN (2010), Best paper award JDDST (2011). Moreover her research activities were founded with PRIN 2002, PRIN 2005, Fondazione Cariplo 2007, Progetto POLGLUMYT POR MARCHE (2008). She takes part in joint research projects with University of Ege (Turkey), University of Szeged (Hungary), Tufts University (Boston, MA, USA), University of Granada (Spain), Federal University of Rio de Janeiro (Brasil) and in research projects founded by pharmaceutical company. She serves as reviewer for several scientific journals. Total number of referred publications: 82 contributions published on scientific journals, 12 book chapters, 3 patents; Hindex: 23 (Scopus), number of citations: 1609 (Scopus) (15/02/2017)


Research Interest

Dr. Giuseppina Sandri research interests concern pharmaceutical development of conventional and controlled release therapeutic systems. Early research works focused on the characterization of polymers, as mucoadhesive and penetration enhancement materials via (trans)mucosal routes other than oral one and in particular via buccal and vaginal routes. A part of the research work served the purpose to clarify the penetration enhancement mechanism of chitosan toward buccal mucosa. In parallel the ocular route was also studied in order to enhance the bioavailability of drugs poorly permeable across the cornea.