Dr. Frank Barone is an accomplished leader with significant experience as Research Director and Professor in Drug Discovery and Academia. Frank has made significant contributions to discovering drugs, to increasing the understanding of drug action and to the biology of several diseases. His strong scientific, management and communication skills have been demonstrated consistently throughout his career. Frank has established a long-term track record of building functional, cohesive research teams that are empowered to meet and exceed their research goals. Currently, in addition to directing Basic Research in Cerebrovascular Disease at SUNY Downstate Medical Center, he advises Medical Students and connects them to Research Mentors for training, supports graduate and medical student education by mentoring students directly, and he is a facilitator in the Medical School (Cardiovascular, Pulmonary and Renal Problem-Based Learning) and teaches in the Graduate School (lectures in Biochemistry-Enzyme Kinetics and in Pharmacology-Receptor Theory and Pharmakokinetics). He has 25 years experience in Drug Discovery functioning as research team leader in developing and executing research strategies from target discovery to drug screening and target validation in disease to marketed drug and post-market drug scientific support; History of maintained/consistent research/resource support in industrial environment for disease target research and compound progression in Discovery Research and as consultant to Pharmaceutical Companies, and in the academic work environment helping to developing research direction, mentoring students at all levels and helping to secure federal research grant support and teaching. He has demonstrated an ability to Integrate Systems Pharmacology/Biology and Translational Medicine into Drug Discovery and Disease Biology Research, with a long standing research background/experience in cardiovascular and cerebrovascular risk factors related to brain changes involved in neurodegeneration, white matter injury and cognitive impairment-dementia.

Dr. Frank BaroneBasic Science, Stroke, Vascular cognitive impairment, white matter injury, Brain injury, Edema, Neuroinflammation, Cognition, Rodent cognition assays, Dementia