Zhihui Liu received his B.S. in biochemistry from Nanjing University in 1995. From 1995 to 1999, he worked for a pharmaceutical company as a research associate. He received a Ph.D. degree from the Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences in 2004. After graduation, he joined the Pediatric Oncology Branch of the NCI as a visiting fellow and research fellow. He currently works in Pediatric Oncology Branch as a staff scientist. He won a NCI Directorís Intramural Innovation Award in 2010. He have been focusing on characterizing tumor suppressor genes in neuroblastoma (NB), and has identified that a chromosome 1p36 gene, CASZ1, is a tumor suppressor in NB. He is working on high-throughput screening of genetic and epigenetic alterations in neuroblastoma to identify novel tumor suppressors, oncogenes and therapeutic targets. The long-term goal is to develop novel therapies for pediatric cancer patients.
Cancer biology; Tumor suppressor genes in neuroblastoma (NB); Genetic and epigenetic alterations in neuroblastoma; Oncogenes; Therapeutic targets.