I received my BS degree in 1996 from Nanchang University, China and MS degree in 1999 from Chinese Academy of Sciences, China and then PhD degree from University of California at Irvine in 2010. I am a member of these professional organizations, Society for Neuroscience (SfN), American Society for Pharmacology and Experimental Therapeutics (ASPET) and The Association for Research in Vision and Ophthalmology (ARVO). I have been reviewed articles for various professional journals, Anti-Cancer Agents in Medicinal Chemistry Applied Microbiology and Biotechnology, Molecular Vision, Plos Biology, Plos Medicine, Clinical and Experimental Pharmacology and Physiology and International Journal of Open Access. I have taught Pharmacy Practice Skills Laboratory 2 / PHAR 7227 at University of North Texas System College of Pharmacy Course and BIO 199 at University of California, Irvine.
I have been working on brain neural transmitter and then changed to eye research. Currently I am focusing my efforts on the relation between retinal degeneration and oxidative stress, particularly the function of gultaredoxin on protection from oxidative stress in retina. Working together with other endogenous antioxidant components in cells, glutaredoxins keep redox homeostasis by alleviate oxidative challenge. The specific disorder of retinal degeneration, age-related macular degeneration (AMD), is affecting 25 million people worldwide. Chronic oxidative stress has been hypothesized as one of the potential pathogenesis factors for AMD. We are using gene knockout mice and light-induced retinal degeneration, primary human and mouse retinal cells and exogenous antioxidant compounds, as models to investigate how glutaredoxins protect retina from oxidative damage.