Dr. Guinn is a Reader at the University of Bedfordshire. Barbara gained her B.Sc. in Genetics from the University of Wales, Aberystwyth in 1991 and a Ph.D. in Medicine from the University of Wales College of Medicine, Cardiff in 1995. She was one of the first Leukaemia Research Fund Gordon Piller Ph.D. students in the year this prestigious award was initiated. she undertook two postdoctoral fellowships at the University of Toronto (Autologous Bone Marrow Transplant Unit, Toronto General Hospital and Department of Immunology). Her research has received support from the Leukaemia & Lymphoma Research, Cancer Research U.K., the Elimination of Leukaemia Fund, Wessex Cancer Trust, Wellcome Trust and British Society for Haematology. She has published over 70 peer-reviewed manuscripts. She is on the editorial board of eleven journals and reviews manuscripts for more than 30 scientific journals on an ad hoc basis.
The characterisation of a urine biomarker for ovarian cancer as well as the identification of novel targets for immunotherapy in acute lymphocytic leukaemia and colon cancer using SEREX, Microarray and RT-PCR; A number of epitopes from these antigens have been inserted into DNA vaccines and tested for suitability for near-future clinical trials; Barbara’s group has also worked on whole cell vaccines for acute myeloid leukaemia and B-cell lymphoma and demonstrated the utility of tetramer arrays as clinical end-point assays.