Dr Debashree Basu earned her PhD in Biochemistry at Center for DNA Fingerprinting and Diagnostics, and Manipal University, India in 2010. The title of her PhD thesis is “Structural and functional studies of stress proteins in Mycobacterium tuberculosis”. She has worked on several pathogenic and non-pathogenic bacteria like Mycobacterium tuberculosis, Mycobacterium smegmatis, Mycobacterium bovis BCG, Escherichia coli and Bacillus subtilis for the past 12 years. She has worked extensively on the nucleoid associated proteins, chaperones and other stress protein, in vivo as well as in vitro. Currently, as a Research Scientist at The University of Texas Medical Branch, USA, her study focuses on the Trans-lesion Synthesis DNA polymerases using bacteria and yeast as her model systems. She believes that the thorough understanding of the mechanistic aspects of these polymerases, will pave the way for discovering new drugs for the treatment of different cancers. Her work has been published in Nucleic Acids Research, PLOS One and Genes to Cells. She is an invited editor of Bioinfo Publications since 2012. She has served as a peer reviewer of PLOS One and Mycobacterial Diseases. She is also an active member of American Association of Medical Writers.
Microbial pathogensis, Microbial engineering, Chaperones, Stress proteins, Nucleoids, DNA-protein interactions, Protein-protein interactions, Polymerases, DNA damage, DNA repair