Dr. Longzhu Cui (M.D., Ph.D.) is Professor and Head of Bacteriology Division, Department of Infection and Immunity, Faculty of Medicine, Jichi Medical University, Japan. Dr. Cui received his Ph.D. in Infectious Disease from The Fourth Military Medical University, Xi’an, China in 1994, followed by two-year postdoctoral fellowship at WHO Collaborating Center for Virus Reference and Research on Heamorrhagic Fever with Renal syndrome (Asan medical center, Seoul, Korea) and came to Japan in 1997. Prior to his arrival at Jichi Medical University, Dr. Cui had served as Assistant Professor, Lecturer andAssociate Professor at Department of Bacteriology, Faculty of Medicine, Juntendo University for 17 years and Vice Director at Research Center for Infections and Antimicrobials, Kitasato Institute for Life Science, Kitasato University for three years. Following early work on the phathogenesis of hantavirus infectious disease and developmentof vaccine, Dr. Cui moved on to studieson Staphylococci and Staphylococcal infectious diseases. His most favorite achievements in the recent workare the clarification of molecular mechanism of vancomycin-resistance in vancomycin-resistant s. aureus (VISA) and findingof a large-scale chromosome flip-flop inversion (highly frequent reversible inversion) responsible for the bacterial phenotype switching. The phenotype switching through the genome flip-flop inversionisan ingenious strategy of bacteria used tosurvive in the adverse environments.
Dr. Cui’s main research interests are in the fields of the pathogenicity and antibiotic resistance of Staphylococcus aureus, the most problematic bacterium in the hospital setting.