Dr. Siddiqui is a geneticist whose research focus is pulmonary and respiratory signaling, oncology, regenerative medicine and tissue engineering. He is currently associated with Northwestern University, Illinois and UQUDENT in Saudi Arabia. He has been a senior faculty in the Department of Medicine, Section of Pulmonary Biology and Critical Care at University of Chicago, Department of Pharmacology at University of Illinois, Chicago and Department of Biochemistry, Molecular Biology and Cell Biology at Northwestern University, Evanston, Illinois. He obtained his Ph.D. from Bombay University for his graduate work performed at the Max-Planck Institute of Experimental Medicine, Gottingen, Germany and the Tata Institute of Fundamental Research, Bombay, India. Dr. Siddiqui has published more than 200 contributions in peer reviewed high impact journals and has authored chapters in books. He has also spent 15 years in Japan as Head of the Laboratory of Molecular Biology at Toyohashi University of Technology and supervised dozens of graduate students for doctoral (Ph.D.) and Masters Degrees. Dr. Siddiqui has several international Patents and has received honors, research grants and awards from Deutsche Forschungsgemeinschaft, Germany, National Institutes of Health, USA, Monbusho, Ministry of Education, Science and Culture Japan and Department of Biotechnology, Ministry of Health, India. He has used genetic model system Caenorhabditis elegans to screen human genetic variants to screen for lung cancer genes and is currently directing a lab on stem cells. He is emeritus member of the Genetics Society of America. He is the founder and associate editor of Nanobiology and editor of several international journals and has reviewed manuscripts for journals focused on genetics and cell biology.
Dr. Siddiqui’s research interests focus on Pulmonary and Respiratory Biology. Dr. Siddiqui has previously investigated the role of endothelial cell permeability in lung barrier function and acute respiratory distress syndrome (ARDS) and regulation of endocytosis via TGF-beta signaling. The role of miRNA in barrier function and lung tumorigenesis has been examined in his lab and aspects of molecular signaling in inflammation and systemic pulmonary disease. Dr. Siddiqui has also performed high throughput screens for novel inhibitors of myosin assembly with a search or therapeutic drugs useful for asthma and respiratory function. Dr. Siddiqui and his colleagues have obtained a US patent for TGF-beta signaling in wound healing and tissue regeneration.