Dr. Yi-Chia Liu received her BSc and MSc in Agricultural Chemistry at National Taiwan University, Taiwan. Her MSc project was to characterise the function of a chitinase from Vibrio parahaemolyticus that may facilitate pathogenesis by the means of host attachment. This work resulted in two international conference presentations in Japan and U.S. Soon after her MSc, she worked in a Molecular Microbiology lab as a research assistant and lab manager. She then took another position as a research scientist in a cancer immunology research group at the Centre of Genomic Medicine, National Taiwan University Hospital, Taiwan, where she developed her research interest in the mechanisms of how human immune system works upon pulmonary infections. For her PhD at University of Nottingham, UK, she was under the supervision of Prof. Luisa Martinez-Pomares focusing on the understanding of chronic pulmonary inflammation by using two pulmonary fibrotic diseases as paradigms. Her PhD work helped elucidate firstly, the contribution of bacterial inter-cellular signalling to human airway epithelial innate immune responses on barrier disruption and cytokine production, and secondly, the tendency of correlation between the systemic immune status of patients with idiopathic pulmonary fibrosis and survival providing potential biomarker algorisms to predict disease progression. In 2015, she joined Dr. Sarah Coulthurstís group at University of Dundee, UK as a post-doctoral researcher funded by The Welcome Trust and investigate the role of a type of bacterial secretion system in pathogenesis and its competence to thrive in multi-organism environment.
The impact of bacterial signalling system on host responses; Host immune responses to chronic bacterial infections at the mucosal barrier; The contribution of a type of bacterial secretion system in pathogenesis and its role for bacterial competence to thrive in the multi-organism environment.