Dr. Parmit Kumar Singh completed his PhD at Centre for Cellular and Molecular Biology (CCMB), Hyderabad, India. He determined the threshold size of duplicated DNA that titrates repeat induced point mutation (RIP) machinery. Moreover, he identified the first wild-isolate strain of Neurospora as a dominant suppressor of meiotic silencing. Both RIP and meiotic silencing are genome defense process in Neurospora. Currently, he is trying to understand the integration preference of HIV-1 and his results, based on one million integration sites of HIV-1 in human cultured cells, showed that HIV-1 has preference for the highly spliced and cancer genes. He is also involved in teaching at the Foundation for Advanced Education in the Science (FAES), and Uniformed Services University of the Health Sciences (USUHS), Bethesda, Maryland, USA.
HIV-1; Retrovirology; Retroelement; Splicing; Chromatin Modification; Genome Analysis; NGS; Genetics and Moelcular Biology.