Dr. Sudhir Rai was raised in Mumbai, India and did his Bachelor of Science at Andhra University, Visakhapatnam in Microbiology, biochemistry and Medical Lab Technology. During his Masters program he had his first exposure to research at the Bioengineering and Environmental Center (BEEC), Indian Institute of Chemical Technology (IICT), in Hyderabad, AP, India. He was enthusiastic in experiencing an in depth research environment. He obtained his Ph.D in 2012 from the Department of Molecular Biology and Biotechnology, at Tezpur University, Assam, India under the guidance of Professor Ashis Kumar Mukherjee. His research was focused on screening environmental samples of North East India for the development of industrially important microbial enzymes. To further improve his scientific skills he transitioned his research from protein chemistry to molecular biology in the lab of Dr.Henry Levin. In his lab, he conducted pilot scale functional genomic screen for identification of host factors required for propagation of retroelements in S.pombe genome. He developed novel genetic assay, which identify host factors required in Tf1-life cycle. He discovered 98 out of 3004 knockout gene deletion library of S.pombe. Based on Tf1-hypothetical model, all 98 gene categorized as Chromatin, Transcription factor, Splicing, DNA Repair, Nuclear Transport, Protein translation, mRNA processing, Vesicle Transport (ER to Golgi, ESCRT), Ubiquitinaton/ Proteasome degradation pathway, Signal Transduction, Metabolic Pathway, Cell division, kinetochore, and Unknown function. Among the various classes of candidates, currently he is exploring the role of DNA repair factors in transposition.
Microbiology; Biochemistry; Bioengineering; Molecular Biology and Biotechnology.