Dr. Alexander Kofinas is a graduate of Athens Health Sciences University (Kapodistrian University) school of medicine, Athens, Greece. After he completed his OBGYN residency at The Brooklyn Hospital Center, Downstate University in NY, he obtained his Maternal Fetal Medicine (MFM) training at Wake Forest School of medicine, Winston-Salem NC, USA. He served as Assistant Professor at the Universities of Wake Forest, University of Pennsylvania York Hospital campus, New York University and recently at Weill Cornell where he holds an appointment as Associate Professor of Clinical Obstetrics and Gynecology. He has taught medical students, residents, and MFM fellows and conducted extensive research in the physiology of the human myometrium, the mechanism of human labor, and the activity of c-AMP phosphodiesterase in non-pregnant and pregnant human myometrium, at rest and in active labor. He recently presented evidence of significantly improved outcomes in patients with unexplained low PAPP-A treated with low molecular weight heparin.
In addition, he has researched the effect of placental location with various pregnancy complications as well as, fetal cerebral vascular responses to vibroacoustic stimulation, fetal cardiovascular responses to chorionic villus sampling (CVS), and research concerning the fetal cardiac and utero-placental vascular systems. Dr. Kofinas is currently researching fetal cardiovascular safety and clinical usefulness of Indomethacin in the prevention of prematurity. He has recently demonstrated that Indomethacin restores cervical length to normal, in patients with premature cervical shortening without any fetal side effects. In his clinical practice, he provides specialized consultative care at Kofinas Perinatal to patients with recurrent pregnancy loss, multiple IVF failures, history of major obstetrical complications and history of fetal demise by paying attention to structural development and vascularization of the placenta as determined by the use of high-resolution ultrasound and power Doppler.
Non-invasive Cardiovascular assessment of the Fetal-maternal unit in pregnancies complicated by placental thrombosis; Utero-placental Doppler evaluation; Fetal cranial Doppler flow studies; Preterm birth prevention: the role of transvaginal Ultrasound and Indomethacin; The role of LMWH in the prevention of complications in patients with abnormal unexplained low maternal serum PAPP-A.