Hana Mahmutefendić Lučin is a full professor at the Department of Physiology and Immunology in the Medical Faculty, University of Rijeka, where she obtained her Ph.D. degree in Biomedicine. Hana Mahmutefendić Lučin is focused on the investigation of endocytic trafficking and membrane dynamics in noninfected cells, and in cells infected with murine cytomegalovirus (MCMV). She has published 26 articles in peer-reviewed scientific journals that are indexed in CC/SCIE database. The majority in Q1/Q2 Journals in the field of cellular biology and virology. Hana Mahmutefendić Lučin has been working in the field of cellular physiology for more than 20 years, first as a young research fellow, and now as the principal investigator. She is also a member of several associations related to her research field. She worked as a reviewer in MDPI Journals, Bioscience Reports, Germs, Journal of Network Medicine and Targeted Therapies, and Clinical Medical Reviews and Case Reports. H. Mahmutefendić Lučin is skilled in laboratory techniques of cell biology, but also the planning and organization of the experiments, and education and mentorship of the young Ph.D. students.
Prof. Hana Mahmutefendić Lučin is focused on mechanisms of cellular regulation of intracellular trafficking (endocytosis, recycling, degradation). She is mostly interested in understanding the mechanisms and dynamics of different recycling processes (from pre-early endosomes, early endosomes, endosomal recycling compartment, trans-Golgi network, and late endosomes). These regulatory mechanisms involve activation of control molecules like those of Rab/Arf GTPases and their effectors, the processes of ubiquitinylation, dynamin scission, etc. We frequently use the model of murine cytomegalovirus (MCMV) infection in our experiments. Namely, as we have published, MCMV remodels the membrane cellular system to prepare the compartment for assembling new viral particles. Therefore, it is a great tool for the reconstruction of normal processes that take place in intact cells.