Dr. Sharma is a post-doctoral researcher at the University of Alabama Birmingham. She obtained her bachelor's in science and a master's in microbiology degree from Kurukshetra University Kurukshetra India. She further pursued a master's in biotechnology and received her Ph.D. from the University of Alabama at Birmingham, where she trained in the Gregory Fleming James Cystic Fibrosis Research Center under the mentorship of Dr. Steven Rowe. Dr. Sharma’s primary research area is in cystic fibrosis (CF) nonsense mutations. Her recent work has helped characterized novel readthrough agents, identified their mechanisms of action, and how combinations of these agents may be used as a novel approach to the treatment of CF patients who carry nonsense mutations. Also, Dr. Sharma has developed and characterized a novel rat model for the CF nonsense mutation G542X, which will provide an in vivo complement to in vitro studies. Dr. Sharma has actively presented her work at national, regional, and local meetings, where she has been awarded multiple times.
Dr. Jyoti Sharma is interested in fields of research that are molecular and cell biology, microbiology, and biochemistry. She is interested in translational clinical research and her present research focuses on identifying novel therapeutic targets for CFTR nonsense mutations.