Dr. Yaohua Yang graduated from Henan Institute of Science and Technology in 2010 and joined the lab of Algal genomics of the Institute of Hydrobiology, Chinese Academy of Sciences and studied on Bioinformatics. After getting his Ph.D. degree in 2016, he joined the Division of Epidemiology, Vanderbilt University Medical Center (VUMC) as a postdoctoral research fellow and since then his research field has turned to genetic epidemiology and molecular epidemiology. During doctoral period, he received intensive training in Bioinformatics, genomics, transcriptomics, proteomics and metagenomics. He worked on multiple research projects of integrative analyses of multi-omics data and building analyses pipelines. He co-led two projects and published two papers as the first or co-first author. The first project was establishment of a proteogenomic analysis and global posttranslational modifications (PTMs) profiling pipeline for prokaryotes, which has been published in PNAS. The second project was construction of an integrative database of omics for a model cyanobacterium, which has been published in Database. After he joined VUMC, he stared to participate in multiple projects of genetic epidemiology and molecular epidemiology. For genetic epidemiology studies, he worked on multiple projects of integrating multi-omics data to discover novel genes and biomarkers for cancer risk and of these projects, the one on ovarian cancer has been published in Cancer Research and the one on breast cancer has been provisionally accepted (under minor revision) by JNCI. He is the first author for both papers. For molecular epidemiology studies, he worked on multiple microbiome projects of investigating the relationship between the microbiome and risk of cancers and evaluating impacts of risk factors of cancers on the microbiome. Of these projects, the one on the oral microbiome and colorectal cancer risk first-authored by him has been published in the International Journal of Cancer.
Dr. Yaohua Yang’s interested in searching for epigenetic biomarkers and casual genes for cancers, including breast cancer, ovarian cancer, lung cancer, colorectal cancer and prostate cancer. Another research focus of Dr. Yaohua Yang is conducting epidemiological studies of the human microbiome, including oral and gut microbiome, to explore the association of microbiome with cancers, including colorectal cancer, gastric cancer and lung cancer, and to evaluate the impacts of risk factors for cancers on the microbiome, including cigarette smoking, obesity, genetics and so on.