Prof. Yun Le is the Harold Hamm Chair in Diabetes Research and Professor of Medicine and Adjunct Professor of Cell Biology and Ophthalmology at the University of Oklahoma Health Sciences Center (OUHSC). He received BS in Biochemistry at Fudan University in china, PhD in Biology/Microbiology at Dalhousie University in Canada, and postdoctoral training in genome biology at Dalhousie and cellular and molecular biology and mouse genetic engineering at National Institutes of Health (NIH) in the United States. Prof. Le started his research career in vision research at OUHSC in 2000 and became an independent investigator there in 2007. He has published over 75 manuscripts in peer-reviewed journals and book chapters and has given over 150 presentations and invited talks. In addition to serving as a reviewer and editorial board member for various journals, Prof. Le was an editor for a special edition of Diabetic retinopathy, Vision Research. Prof. Le also reviews research grant applications regularly for NIH, British Medical Research Council, and other funding agencies.
Prof. Yun Le’s research interests include mechanisms of diabetes-induced breakdown of both the inner and outer blood-retina barriers and alteration of retinal neurons, age-related macular degeneration, and photoreceptor death and protection, pathobiology of Müller glia, technological development in generating gene-modified animal models, preclinical treatment of retinal diseases, and retinal regeneration.