Dr. Loiy Ahmed Hassan completed a Bachelor of Science (Chemistry &Botany) in 2004 at University of Khartoum, Sudan. In year 2009, he completed his MSc in Phytochemistry and biological activities in University of Khartoum, Sudan. He graduated with a PhD in the field of Pharmacology in school Pharmaceutical Sciences, Universiti Sains Malaysia (USM) in 2016. He spent most of his research at USM in cancer biology and drug discovery. He was also appointed as a postdoctoral researcher at Department of Pharmacology, School of Pharmaceutical Sciences, Universiti Sains Malaysia (USM) for six months. Most of Loiy’s research interest focuses on development of drugs that target angiogenesis for the treatment of cancer. Many of his research activities in this field are centered towards natural products particularly into transforming herbs into pharmaceuticals. Dr Loiy is passionate in affordable chemotherapeutic medicine for the bottom billions.
Loiy Elsir Ahmed Hassan Research Interests are Investigation of antiangiogenic (in vitro, ex vivo and in vivo) activities of new experimental and well-established chemotherapeutic drugs or their combination, also understanding of molecular interactions between active antitumor drugs and their molecular and cellular targets in the signal transduction pathways they participate to. Antitumor in vivo (of botanical herbs as well as natural and synthetic compounds) using different animals models to establish comprehensive preclinical data of the compounds and the standardized extract as step for clinical trials, in addition to anti-inflammatory evaluation of active constituents (in vitro and in vivo) and its correlation with angiogenesis and cancer progression. Anticancer study on cytotoxic/cytostatic activity of new experimental and well-established chemotherapeutic drugs or their combination based on a useful model for the study of signal transduction pathways, as targets for new anticancer drugs and the elucidation of their mechanism of action at both molecular and cellular level. Cell cycle analysis, study of signal transduction pathways and their relation to apoptosis and to correlate the novel agents with cellular entities of cancer cells or the protein targets of other diseased cells Study of the genes that are related to the growth or suppression of cancer growth. Development of new drugs with improved toxicity pattern, increased anticancer activity and better selectivity, through modifying the structure of known functional molecules. Virtual high-throughput screening and study of the structure of the active or binding site of a plethora of new all-promising target-proteins in the research field of cancer therapy. Discovery of new therapeutic strategies based in new knowledge about molecular modeling and combinatorial chemistry (computer aided drug design).