Dr. Prashant Bommi (MS. Ph.D. in Oral Sciences) was born in India. After finishing his Masterís degree in agricultural science in India, he joined Murray State University, Murray, Kentucky to study biotechnology and gradated in Agronomy with minor in Molecular Genetics. He received his Ph.D. in Oral Sciences from College of Dentistry, University of Illinois at Chicago. During his doctoral studies, he worked on a variety of projects including human papillomavirus (HPV) and DNA damage in Oral Head and Neck cancer. He presented his work on HPV during oral presentation at 2017 IADR/AADR/CADR held at San Francisco, CA., in March 2017. His work in oral cancer biology on damaged DNA binding protein and regulation of HIF1A will have a huge impact as a therapy target. His work has uncovered the role of DNA damaged binding protein in acting as a barrier to metastasis by inhibiting the key genes involved in epithelial to mesenchymal transition (EMT) that promote invasiveness and motility to cancer cells. His goal is to find new biomarkers for early detection of Oral cancer since this cancer is asymptomatic during the onset and is only detected after metastasizing to other tissues in the body.
Nucleotide excision repair, DNA damage, Tobacco metabolites, Chemical carcinogens, Oral Pathobiology, Oral Cancer Biology, Head and Neck Squamous Cell Carcinoma (HNSCC), Hypoxia, Oral lesions, biomarkers, early detection, High-risk Human papillomavirus (HPV), Senescence.