Research Article
Volume 7 Issue 7 - 2022
Outcomes of a Stereotactic Protocol for Canine Nasal Tumors with a Combined Dose to Head and Neck Lymph Nodes: 10 Cases (2016 - 2020)
IF Vanhaezebrouck1*, CR Mendez-Valenzuela1, GE Moore2 and JM Plantenga1
1Service of Radiation Oncology, Department of Small Animal Science, College of Veterinary Medicine, Purdue University, West Lafayette, IN, USA
2Service of Internal Medicine, Department of Small Animal Science, College of Veterinary Medicine, Purdue University, West Lafayette, IN, USA
*Corresponding Author: IF Vanhaezebrouck, Service of Radiation Oncology, Department of Small Animal Science, College of Veterinary Medicine, Purdue University, West Lafayette, IN, USA.
Received: May 18, 2022; Published: June 29, 2022




Abstract

Objectives:  To present results from stereotactic radiation on a linear accelerator for nasal cavity tumors in canine patients. In addition results from mandibular and retropharyngeal lymph nodes receiving a prophylactic dose of radiation are included.

Methods: Medical records were analyzed for dogs treated with stereotactic radiation treatment for nasal tumors.  Standardized treatment was a total of 24Gy delivered in three treatments (8Gy) every other day. In addition head and neck lymph nodes received 5Gy at the same time. The planning target volume margins were less than or equal to 3mm. Dose optimization was accomplished by following the inverse planning method.

Results: Ten dogs met the inclusion criteria.  Eight of the dogs had stage 3 cancer and two of the dogs had stage 1 (Adams modified). The median overall survival for the series was 432 days.  Minimal acute and late effects were observed.  These were defined as no higher than grade 1 toxicity using the Veterinary Radiation Treatment Oncology Group classification system. 

Clinical Significance:  Hypofractionated intensity-modulated radiotherapy with a dose of 8Gy every other day might be a reasonable treatment option for dogs with nasal cavity stage 1 - 3 cancer. Patient’s stage selection is essential before enrolling them with hypofractionated treatment for nasal tumors when treated with linear accelerators not specifically designed for those techniques. Physics criteria selection, such as a sharp gradient index and a conformity index close to one, improves the treatment dosimetry quality.  Further study is needed on the lymph nodes treatment relevance and the enrollment of a larger group to confirm the findings of this study.

 

Keywords: Stereotactic Radiation; Nasal Cavity Tumor

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Citation: IF Vanhaezebrouck., et al. “Outcomes of a Stereotactic Protocol for Canine Nasal Tumors with a Combined Dose to Head and Neck Lymph Nodes: 10 Cases (2016 - 2020)”. EC Veterinary Science 7.7 (2022): 15-26.

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