Research Article
Volume 5 Issue 8 - 2020
A Simulation Study on the Effects of Founding Population Size and Number of Alleles Per Locus on the Observed Population Genetic Profile: Implications to Broodstock Management
Nur Jannah Kamarudin1,2, Victor CC Wang1,2, Xue Ting Tan1,2, Avettra Ramesh1,2, Shermaine SM Chew1,2, Madhurya V Murthy1,2, Nikita V Yablochkin1,2, Karthiga Mathivanan1,2 and Maurice HT Ling1,2,3*
1Department of Applied Sciences, Northumbria University, United Kingdom
2School of Life Sciences, Management Development Institute of Singapore, Singapore
3HOHY PTE LTD, Singapore
*Corresponding Author: Maurice HT Ling, School of Life Sciences, Management Development Institute of Singapore, Singapore.
Received: July 04, 2020; Published: July 31, 2020




Abstract

Loss of genetic variability in small population, known as founder effect, is commonly seen in aquaculture, where broodstocks are not routinely supplemented from the wild, leading to detrimental effects. Yet, the relationship between founding population size and observed population genetic profile is not clear. Here, the effects of founding population size and number of alleles per locus on the observed population genetic profile across multiple generations were examined using simulation. Our results suggest that the number of alleles per locus (p-value = 1.2E-102) and generation counts (p-value < 1E-240) are significant factors in genetic drift but not founding population size (p-value = 0.12). This suggests that genetic drift occurs regardless of population sizes, which may have implications in broodstock management to constantly minimize the impact of genetic drift regardless of broodstock population.

Keywords: Genetic Variability; Founder Effect; Broodstock Population; Alleles Per Locus

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Citation: Maurice HT Ling., et al. “A Simulation Study on the Effects of Founding Population Size and Number of Alleles Per Locus on the Observed Population Genetic Profile: Implications to Broodstock Management”. EC Veterinary Science 5.8 (2020): 176-180.

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