Research Article
Volume 5 Issue 3 - 2020
Phytochemical Screening of Chrisophyllum argyrophillum Hiem. a Plant Used as a Healer in the Village of Vila Franca, Huambo - Angola
Armindo Paixão António1*, Bernardo Chicola1, Justo dos Santos1, Cristóvão Simões1, Antonia Virginia Pedro1, Diassonama Lucombo Maria1 and Luz María Sanchez2
1Faculty of Veterinary Medicine, José Eduardo dos Santos University, Huambo, Angola
2National Center for Agricultural Health (CENSA), Jamaica Road and National Highway, Mayabeque, Cuba
*Corresponding Author: Armindo Paixão António, Faculty of Veterinary Medicine, José Eduardo dos Santos University, Huambo, Angola.
Received: December 16, 2019; Published: February 29, 2020


With the objective of determining the secondary metabolites of the species Chrysophyllum argyrophyllum Hiem, plant used in the community of Vila Franca in the municipality of Londuimbali province of Huambo, Angola, phytochemical screening was performed, for this, leaves and stem hull were collected and subsequently the leaves were dried in the open air in shade and the stem hull dried directly in the sun. After drying, the leaves and stems were sprayed in a traditional mortar and were screened, which allowed the separation of coarse particles from the fines, which were later transported to CENSA, Cuba where the primary phytochemical screening was carried out. Thus, secondary metabolites were detected such as tannins, alkaloids, flavonoids, leucoanthocyanidins, free phenols, primary and secondary amines that generally presented in appreciable quantities, no quinones, triterpenes and/or steroids and lactonic rings were detected.

Keywords: Screening; Leaves; Stems; C. argyrophyllum; Huambo; Angola


  1. Brazil Ministry of Health. Secretariat of Science, Technology and Strategic Inputs. Department of Pharmaceutical Assistance. National Policy and Program for Medicinal and Phytotherapeutic Plants/Ministry of Health, Secretariat of Science, Technology and Strategic Inputs, Department of Pharmaceutical Assistance - Brasília: Ministry of Health (2016): 190.
  2. Catarino L., et al. “Tropical flora and vegetation: Guinea-Bissau experiences and new challenges for Angola”. 1st National Flora and Vegetation Meeting of Angola 24 (2011).
  3. Soares MO., et al. “Biotherapeutic activity of Angolan medicinal plants”. 1st National Flora and Vegetation Meeting of Angola (2011): 22.
  4. Pochettino ML., et al. “Traditional botanical knowledge, commercial circulation and consumption of medicinal plants in an urban area of Argentina”. Latin American and Caribbean Bulletin of Medicinal and Aromatic Plants 7 (2018): 141-148.
  5. Portelinha MK., et al. “Reinterpreting medicinal plants from the yinyang framework of traditional Chinese medicine”. Journal of Nursing and Health 3.7 (2017): 177-310.
  6. Maia ACF., et al. “Phytotherapy under the optics of health professionals in Brazil in the last 10 years”. Gaita Scientia 10.4 (2016): 658-670.
  7. Cunha AP., et al. “Plants and plant products in herbal medicine. Colouste Gulbenkian Foundation. Education and Scholarship Service”. Lisbon - Portugal 2 (2006): 21-54.
  8. Zatta M. The Pharmacy of Nature, 20th edition. São Paulo, Paulinas, Series II (2007): 141.
  9. AC Diniz. “Mesological characteristics of Angola”. IPad. 2nd edition, Lisbon (2006): 197.
  10. Chigodi MO., et al. "Phytochemical screening of Agave sisalana perrine leaves (waste)". International Journal of Applied Biology and Pharmaceutical Technology 4.4 (2013): 200-204.
  11. García DE. “Evaluation of the main factors influencing the phytochemical composition of Morus alba (Linn.)”. Thesis presented in option to the academic title of Master in Pastures and Forrajes. EEPF “Indian Hatuey”. Matanzas, Cuba. (2003): 97.
  12. Camacho-Campos C., et al. “Phytochemical and antibacterial properties of extracts of Tagetes erecta L. Center for Biotechnological Studies”. Universidad de Matanzas Matanzas, Cuba (2018): 13.
  13. Kuklinski C. “Pharmacognosy: Study of drugs and medicinal substances of natural origin”. In: NAVARRO-SCHMIDT.D. Chemical, Biological and Pharmacological Study of the Species of Allamanda blanchetti and Alamanda schottii to Obtain Bioactive Fractions and Therapeutic Potential Molecules. PhD Thesis (2005): 5.
  14. Saumell C., et al. “Further alternatives to chemical control of gastrointestinal nematodes in domestic animals. Book of Resistance to Internal Antiparasitics in Argentina”. Parasitology and Parasitic Nursing Area, Faculty of Veterinary Sciences (2010): 80-84.
  15. Alemán Y., et al. “Larvicidal activity of extracts of Rhizophora mangle L. against gastrointestinal strongylides of sheep”. Revista de Salud Animal 33.2 (2011): 111-115.
  16. Yoshihara E., et al. “Anthelmintic effect of condensed tannins on sheep gastrointestinal nematodes”. Network of Scientific Journals of Latin America 34.6 (2013): 3935-3950.
  17. Cushnie T and Lamb AJ. “Recent advances in understanding the antibacterial properties of flavonoids”. International Journal of Antimicrobial Agents (2011): 99-107.
  18. Serpa R., et al. “In vitro antifungal activity of the flavonoid baicalein against Candida species”. Journal of Medical Microbiology 61 (2012) 1704-1709.
  19. Friedman M. “Overview of antibacterial, antitoxin, antiviral, and antifungal activities of tea flavonoids and teas”. Molecular Nutrition and Food Research (2007): 116-134.
  20. Sandhar HK., et al. “Review of Phytochemistry and Pharmacology of Flavonoids”. Internationale Pharmaceutical Sciences 1.1 (2011): 25-41.
  21. García-Lafuente, A., et al. “Flavonoids as anti-inflammatory agents: implications in cancer and cardiovascular disease”. Inflammation Research (2009): 537-552.
  22. Muñoz Cendales DR and Cuca Suarez LE. “Cytotoxic compounds of plant origin and their relationship to apoptosis inhibiting proteins (IAP)”. Revista Colombiana de Cancerología 20.3 (2016): 124-34.
  23. Ishida H., et al. “Nutritive evaluation on chemical components of leaves, stalks, and stems of sweet potatoes (Ipomoea potatoesPoir)”. Food Chemistry 68 (2000): 359-367.
  24. Henao RSC., et al. “Bactericidal activity of acidic extracts of Lippia alba (Mill.) N.E. Brown against Helicobacter pylori”. Colombian Associations of Gastroenterology, Digestive Endoscopy, Coloproctology and Hepatology (2011): 82-87.
  25. Passion A., et al. “Phytochemical screening of methanolic extracts of Croton mubango Müll Arg. and Indigofera hendecaphlla Jacq. from the province of Huambo, Angola”. Journal of Dairy and Veterinary Sciences 11.3 (2019): 3.
Citation: Armindo Paixão António., et al. “Phytochemical Screening of Chrisophyllum argyrophillum Hiem. a Plant Used as a Healer in the Village of Vila Franca, Huambo - Angola”. EC Nutrition 5.3 (2020): 01-05.

PubMed Indexed Article

EC Pharmacology and Toxicology
LC-UV-MS and MS/MS Characterize Glutathione Reactivity with Different Isomers (2,2' and 2,4' vs. 4,4') of Methylene Diphenyl-Diisocyanate.

PMID: 31143884 [PubMed]

PMCID: PMC6536005

EC Pharmacology and Toxicology
Alzheimer's Pathogenesis, Metal-Mediated Redox Stress, and Potential Nanotheranostics.

PMID: 31565701 [PubMed]

PMCID: PMC6764777

EC Neurology
Differences in Rate of Cognitive Decline and Caregiver Burden between Alzheimer's Disease and Vascular Dementia: a Retrospective Study.

PMID: 27747317 [PubMed]

PMCID: PMC5065347

EC Pharmacology and Toxicology
Will Blockchain Technology Transform Healthcare and Biomedical Sciences?

PMID: 31460519 [PubMed]

PMCID: PMC6711478

EC Pharmacology and Toxicology
Is it a Prime Time for AI-powered Virtual Drug Screening?

PMID: 30215059 [PubMed]

PMCID: PMC6133253

EC Psychology and Psychiatry
Analysis of Evidence for the Combination of Pro-dopamine Regulator (KB220PAM) and Naltrexone to Prevent Opioid Use Disorder Relapse.

PMID: 30417173 [PubMed]

PMCID: PMC6226033

EC Anaesthesia
Arrest Under Anesthesia - What was the Culprit? A Case Report.

PMID: 30264037 [PubMed]

PMCID: PMC6155992

EC Orthopaedics
Distraction Implantation. A New Technique in Total Joint Arthroplasty and Direct Skeletal Attachment.

PMID: 30198026 [PubMed]

PMCID: PMC6124505

EC Pulmonology and Respiratory Medicine
Prevalence and factors associated with self-reported chronic obstructive pulmonary disease among adults aged 40-79: the National Health and Nutrition Examination Survey (NHANES) 2007-2012.

PMID: 30294723 [PubMed]

PMCID: PMC6169793

EC Dental Science
Important Dental Fiber-Reinforced Composite Molding Compound Breakthroughs

PMID: 29285526 [PubMed]

PMCID: PMC5743211

EC Microbiology
Prevalence of Intestinal Parasites Among HIV Infected and HIV Uninfected Patients Treated at the 1o De Maio Health Centre in Maputo, Mozambique

PMID: 29911204 [PubMed]

PMCID: PMC5999047

EC Microbiology
Macrophages and the Viral Dissemination Super Highway

PMID: 26949751 [PubMed]

PMCID: PMC4774560

EC Microbiology
The Microbiome, Antibiotics, and Health of the Pediatric Population.

PMID: 27390782 [PubMed]

PMCID: PMC4933318

EC Microbiology
Reactive Oxygen Species in HIV Infection

PMID: 28580453 [PubMed]

PMCID: PMC5450819

EC Microbiology
A Review of the CD4 T Cell Contribution to Lung Infection, Inflammation and Repair with a Focus on Wheeze and Asthma in the Pediatric Population

PMID: 26280024 [PubMed]

PMCID: PMC4533840

EC Neurology
Identifying Key Symptoms Differentiating Myalgic Encephalomyelitis and Chronic Fatigue Syndrome from Multiple Sclerosis

PMID: 28066845 [PubMed]

PMCID: PMC5214344

EC Pharmacology and Toxicology
Paradigm Shift is the Normal State of Pharmacology

PMID: 28936490 [PubMed]

PMCID: PMC5604476

EC Neurology
Examining those Meeting IOM Criteria Versus IOM Plus Fibromyalgia

PMID: 28713879 [PubMed]

PMCID: PMC5510658

EC Neurology
Unilateral Frontosphenoid Craniosynostosis: Case Report and a Review of the Literature

PMID: 28133641 [PubMed]

PMCID: PMC5267489

EC Ophthalmology
OCT-Angiography for Non-Invasive Monitoring of Neuronal and Vascular Structure in Mouse Retina: Implication for Characterization of Retinal Neurovascular Coupling

PMID: 29333536 [PubMed]

PMCID: PMC5766278

EC Neurology
Longer Duration of Downslope Treadmill Walking Induces Depression of H-Reflexes Measured during Standing and Walking.

PMID: 31032493 [PubMed]

PMCID: PMC6483108

EC Microbiology
Onchocerciasis in Mozambique: An Unknown Condition for Health Professionals.

PMID: 30957099 [PubMed]

PMCID: PMC6448571

EC Nutrition
Food Insecurity among Households with and without Podoconiosis in East and West Gojjam, Ethiopia.

PMID: 30101228 [PubMed]

PMCID: PMC6086333

EC Ophthalmology
REVIEW. +2 to +3 D. Reading Glasses to Prevent Myopia.

PMID: 31080964 [PubMed]

PMCID: PMC6508883

EC Gynaecology
Biomechanical Mapping of the Female Pelvic Floor: Uterine Prolapse Versus Normal Conditions.

PMID: 31093608 [PubMed]

PMCID: PMC6513001

EC Dental Science
Fiber-Reinforced Composites: A Breakthrough in Practical Clinical Applications with Advanced Wear Resistance for Dental Materials.

PMID: 31552397 [PubMed]

PMCID: PMC6758937

EC Microbiology
Neurocysticercosis in Child Bearing Women: An Overlooked Condition in Mozambique and a Potentially Missed Diagnosis in Women Presenting with Eclampsia.

PMID: 31681909 [PubMed]

PMCID: PMC6824723

EC Microbiology
Molecular Detection of Leptospira spp. in Rodents Trapped in the Mozambique Island City, Nampula Province, Mozambique.

PMID: 31681910 [PubMed]

PMCID: PMC6824726

EC Neurology
Endoplasmic Reticulum-Mitochondrial Cross-Talk in Neurodegenerative and Eye Diseases.

PMID: 31528859 [PubMed]

PMCID: PMC6746603

EC Psychology and Psychiatry
Can Chronic Consumption of Caffeine by Increasing D2/D3 Receptors Offer Benefit to Carriers of the DRD2 A1 Allele in Cocaine Abuse?

PMID: 31276119 [PubMed]

PMCID: PMC6604646

EC Anaesthesia
Real Time Locating Systems and sustainability of Perioperative Efficiency of Anesthesiologists.

PMID: 31406965 [PubMed]

PMCID: PMC6690616

EC Pharmacology and Toxicology
A Pilot STEM Curriculum Designed to Teach High School Students Concepts in Biochemical Engineering and Pharmacology.

PMID: 31517314 [PubMed]

PMCID: PMC6741290

EC Pharmacology and Toxicology
Toxic Mechanisms Underlying Motor Activity Changes Induced by a Mixture of Lead, Arsenic and Manganese.

PMID: 31633124 [PubMed]

PMCID: PMC6800226

EC Neurology
Research Volunteers' Attitudes Toward Chronic Fatigue Syndrome and Myalgic Encephalomyelitis.

PMID: 29662969 [PubMed]

PMCID: PMC5898812

EC Pharmacology and Toxicology
Hyperbaric Oxygen Therapy for Alzheimer's Disease.

PMID: 30215058 [PubMed]

PMCID: PMC6133268

News and Events

July Issue Release

We always feel pleasure to share our updates with you all. Here, notifying you that we have successfully released the July issue of respective journals and the latest articles can be viewed on the current issue pages.

Submission Deadline for Upcoming Issue

ECronicon delightfully welcomes all the authors around the globe for effective collaboration with an article submission for the upcoming issue of respective journals. Submissions are accepted on/before July 19, 2022.

Certificate of Publication

ECronicon honors with a "Publication Certificate" to the corresponding author by including the names of co-authors as a token of appreciation for publishing the work with our respective journals.

Best Article of the Issue

Editors of respective journals will always be very much interested in electing one Best Article after each issue release. The authors of the selected article will be honored with a "Best Article of the Issue" certificate.

Certifying for Review

ECronicon certifies the Editors for their first review done towards the assigned article of the respective journals.

Latest Articles

The latest articles will be updated immediately on the articles in press page of the respective journals.