Review Article
Volume 8 Issue 2 - 2020
Pharmacological Management of Obesity
Mohamad Mohsen Motawea1*, Halima Mohammed Saeed M Al-Jadaani2, Abdullah Ahmed Almayouf3, Reham Abdulaziz Altaifi2, Mohammed Abdullah Al Ghazal4, Kholoud Khaled Momenah5, Nasser Mohammed Y Alamri6, Mohammed Sami Basubrain7, Ghadi Abdulaziz Jastaniah7, Lama Rashid Elessawi8 and Abdullah Musaad Alahmadi9
1Abdul Latif Jameel Hospital for Medical Rehabilitation, Saudi Arabia
2Batterjee Medical College, Saudi Arabia
3King Faisal University, Saudi Arabia
4King Fahad Hospital, Saudi Arabia
5Administration of Home Health Care, Saudi Arabia
6Alyarmook West Primary Health Center, Saudi Arabia
7Ibn Sina National College for Medical Studies, Saudi Arabia
8Albalad Primary Healtg Care, Saudi Arabia
9Madinah General Hospital, Saudi Arabia
*Corresponding Author: Mohamad Mohsen Motawea, Abdul Latif Jameel Hospital for Medical Rehabilitation, Saudi Arabia.
Received: January 03, 2020; Published: January 22, 2020




Abstract

Introduction: A major pandemic of the 21st-century obesity is in both developed and developing countries, which is increasingly contributing to chronic diseases associated with it and draining economic resources. Despite the overwhelming amount of information regarding obesity and the morbidity and mortality associated with it, the number of obese individuals rise each year. The dangers of being obese are far more alarming than most people realize. Obesity significantly increases the risk of diabetes mellitus, hypertension, coronary artery disease, dyslipidaemia, stroke, gallbladder disease, osteoarthritis, gastroesophageal reflux disease, sleep apnoea, lower back pain, asthma. Obesity is also known to increase the risk of cancers of colon, endometrium, prostate, and breast. Using pharmacotherapy for weight management is consistent in treating obesity as a chronic disease that requires a multifaceted approach, including behavioral intervention, medical intervention, and dietary change. The current guideline recommends that a person who fails to respond to lifestyle intervention with BMI more than 30 kg/m2 with obesity-related comorbidity should opt for weight loss medical treatment.

Aim of the Study: Aim of study is to understand pharmacological intervention of weight loss management.

Methodology: The review is comprehensive research of PUBMED from the year 1998 to 2017. 

Conclusion: The benefits of weight reductions are irrefutable, and lifestyle intervention aimed at promoting weight loss remains the cornerstone of the treatment. But despite all most patients are unable to achieve 10kg weight loss targets and maintenance. Thus, pharmacotherapy is one valuable option in weight loss management with growing acceptance to it. Several drugs are approved and currently used, but long-term data on safety and efficacy in cardiovascular conditions remain warranted. Apart from this the health care practitioners should consider the weight effects of pharmacotherapy in management of obesity-related comorbidities with the use of weight-neutral or weight-reducing medication that can complement patient’s desire and for healthier lifestyles.

Keywords: Weight Loss Management; Pharmacotherapy

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Citation: Mohamad Mohsen Motawea., et al. “Pharmacological Management of Obesity”. EC Pharmacology and Toxicology 8.2 (2020): 01-06.

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