Abstract

Medicinal plants have long been known to prevent, treat, and improve the health of people around the world including in Indonesia. Medicinal plants are also known as a source of raw materials for medicines and cosmetics. One of the plants that have the prospect to be used as cosmetic ingredients is Stelechocarpus burahol. In Indonesia, the fruits of this plant has been used traditionally as a deodorant and deodorant by the family of queens and princesses in the kingdoms of Yogyakarta and Solo. The use of Stelechocarpus burahol fruit can scent body odor, including sweat, urine, and feces. This article will review the bioactivity of burahol and the prospects of Stelechocarpus burahol as oral deodorant.

Keyword: Burahol; Stelechocarpus burahol; Bioactivity; Halitosis; Oral Deodorant

References

1. Sunarto AT. “Stelechocarpus burahol (Blume) Hook.f. and Thomson”. In: Verheij EWM, Coronel RE (editions.) Plant resources of South-East Asia. No. 2: Edible fruits and nuts. Prosea Foundation, Bogor (1992): 290-291.
2. Lim TK. “Edible Medicinal and Non-Medicinal Plants”. Volume 1, Fruits (2012).
3. Tree and fruit of Stelechocarpus burahol.
4. Heyne K. “Useful Plants Indonesia”. 2^nd Yayasan Sarana Wana Jaya. The Ministry of Forestry, Jakarta (1987): 765.
5. Heriyanto NM and Garsetiasih R. “Existence of Stelechocarpus burahol (BB) Hook”. F. and Th, ecological study of burahol tree (Stelechocarpus burahol) at Meru Betiri National Park, East Java” (2012).
6. “Ecology of Kepel (Stelechocarpus burahol (Blume) Hook. F. and Thomson) In Purwodadi Botanical Garden”. Proceeding of International Conference on Medicinal Plants, Surabaya, Indonesia (2010).
7. Tati R., et al. “Research Statues and Conservation Effort of Burahol Species (Stelechocarpus burahol (Blume) Hook and Thomson)”. Proceeding International Conference on Medicinal Plants, Surabaya, Indonesia 21-22 (2010): 166.
8. Verheij EWM and Coronel RE. “Plant resources of South East Asia 2: Edible fruits and nuts”. Prosea, Bogor (1997).
9. , et al. “Anti-hyperuricemic activity of the kepel [Stelechocarpus burahol (Bl.) Hook. F. and TH.] leaves extract and xanthine oxidase inhibitory study”. International Journal of Pharmacy and Pharmaceutical Sciences 2.2 (2010): 122-127.
10. Sunarni T., et al., “Antioxidant–free radical scavenging of flavonoid from The Leaves of Stelechocarpus burahol (Bl.) Hook f. and Th”. Indonesian Journal of Pharmacy3 (2007): 111-116.
11. Batubara I., et al. “Kepel, potency of kepel (Stelechocarpus burahol) as cyclooxygenase-2 inhibitor”. Proceeding of International Conference on Medicinal Plants - Surabaya, Indonesia 21-22 July, (2010): 282.
12. Sunardi C., et al. “Identification of cytotoxic alkaloid phenanthrene lactams from Stelechocarpus burahol”. ITE Letters on Batteries, New Technologies and Medicine3 (2003): 328-331.
13. Pribadi P., et al. “Utilization of squeeze of kepel fruit (Stelechocarpus burahol (Blume) Hook and Thomson) as wound antiseptic”. Pharmasiana2 (2014): 177-183.
14. Sunardi C., et al. “Isolation and identification toxic oxoaporphinoid alkaloid from Stelechocarpus burahol Hook F. and Thoms. stem bark (Annonaceae)”. Proceeding of International Conference on Medicinal Plants - Surabaya, Indonesia 21-22 (2010): 160.
15. Darusman HS., et al. “Indonesian kepel fruit (Stelechocarpus burahol) as oral deodorant”. Research Journal of Medicinal Plants2 (2012): 180-188.
16. Amin A., et al. “Halitosis activity against volatile sulfur compound of methyl mercaptan component from burahol (Stelechocarpus burahol) fruit extract”. Asian Journal of Pharmaceutical and Clinical Research5 (2017): 116-119.
17. Mun’im A., et al. “Effect of burahol [Stelechocarpus burahol (Blume) Hook.f. and Thomson] fruits extract mouthwash on mouth bad deodorization”. Indian Journal of Traditional Knowledge3 (2017): 431-436.
18. , et al. “Identification of standard parameters of kepel leaves [Stelechocarpusburahol (BL.) Hook. F. and TH.] and the extract as raw material for anti-hyperuricemic medicaments”. Asian Journal of Pharmaceutical and Clinical Research 4.1 (2011): 149-153.
19. Hakim AR., et al. “Antihyperuricemic activity of the Kepel [Stelechocarpus burahol (Bl.) Hook. F. and Th.] leaves extract and xanthine oxidase inhibitory study”. International Journal of Pharmacy and Pharmaceutical Science2 (2010): 123-127.
20. Sunarni T., et al. “Antihyperuricemic activity of four plants annonaceae using hyperuricemic rat model and enzyme assay”. Asian Journal of Pharmaceutical and Clinical Research6 (2015): 250-253.
21. Sunarni T., et al. “Constituent and antihyperuricemic activity of Stelechocarpus burahol leaves subfractions”. Asian Journal of Pharmaceutical and Clinical Research4 (2017): 435-439.
22. Tisnadjaja D., et al. “Study of burahol (Stelechocarpus burahol) (Blume) Hook and Thomson) as an antioxidative compounds containing fruit”. Biodiversitas2 (2006): 199-202.
23. Suwandi AO., et al. “Effect of kepel leaves’ extract (Stelechocarpus burahol (bl) Hook F. and Th.) concentration on the antioxidant activity and its physical properties within cream formulation”. Journal of Traditional Medicine2 (2012): 27-33.
24. Sunardi C., et al. “Antiimplantation effect of ethanol extract from ripening burahol flesh (Stelechocarpus burahol Hook f. and Thomson) on white female rats Wistar strain”. Pharmaceutical Science Magazine1 (2010): 1-8.
25. Suparmi S., et al. “Anti-Implantation Activity of Kepel (Stelechocarpus burahol) Pulp Ethanol Extract in Female Mice”. The Journal of Pure and Applied Chemistry Research3 (2015): 94-99.
26. , et al. “Kaempferol from Stelechocarpus burahol, (Bl.) hook f. and Th. leaves and xanthine oxidase inhibition activity”. Asian Journal of Pharmaceutical and Clinical Research 9.1 (2016): 325-328.
27. , et al. “In silico analysis of xanthine oxidase inhibitor of ethyl acetate fraction of ethanolic extract of Stelechocarpus burahol (Bl.) Hook F. and TH. Leaves”. Asian Journal of Pharmaceutical and Clinical Research 10.5 (2017): 112-115.
28. Alvernita G. “The Histopathology of mice liver treated by kepel (Stelechocarpus burahol) suspension intragastrically for 14 days”. (2011).
29. Amin A., et al. “Antimicrobial Activity of Ethyl Acetate Fraction from Stelechocarpus burahol Fruit against Oral Bacteria and Total Flavonoids Content”. Journal of Young Pharmacists2 (2018): s97-s100.
30. Priastini R and Rumiati F. “Effect of Additional antioxidant of fruit extract of kepel (Stelechocarpus burahol) in semen diluent to the quality of Rex Rabbit’s Spermatozoa”. Proceeding of International Conference on Medicinal Plants - Surabaya, Indonesia 21-22 (2010): 80.
31. Soen Bing A., et al. “Efficacy of lozenges containing kepel fruit (Stelechocarpus burahol) extract for controlling oral malodor”. International Journal of Applied Pharmaceutics1 (2018).
32. Indriani S., et al. “Antibacterial activity of flavonoid fron kepel (Stelechocarpus burahol) leaves against Staphylococcus epidermidis”. International Journal of Pharmacy and Pharmaceutical Science10 (2017): 292-296.
33. Rahminiwati M., et al. “Anti-acne potency of kepel (Stelechocarpus burahol)’s leaves and fruits”. Proceeding of International Conference on Medicinal Plants, Surabaya, Indonesia (2010): 287-291.
34. Anggara ED., et al. “Antifungal activity test of ethanol fraction of kepel leaves (Stelechocarpus burahol, Hook F and Th.) infusion against Candida albicans”.
35. Shulgin AT and Perry WE. “The Simple Plant Isoquinolines”. Transform Press: Berkeley, CA, USA. (2012).
36. Sunardi C. “Structure of steroids in Stelechocarpus burahol Hook f. and Thomson Stem Bark”. Journal of Indonesian Medicinal Plants2 (2010): 115-117.
37. Sunardi C., et al. “Structure of Steroids in Stelechocarpus burahol Hook F. and Thomson Stem Bark”. Proceeding of International Conference on Medicinal Plants - Surabaya, Indonesia (2010): 164.
38. Turkington C and Dover JS. “The encyclopedia of skin and skin disorders”. (3rd edition.). Kindle Edition, New York (2007): 363.
39. Lundström., et al. “Functional Neuronal Processing of Human Body Odors”. Pheromones. Academic Press (2010).
40. Dunbar R and Barret L. “The Oxford Handbook of Evolutionary Psychology”. Oxford University Press (2007).
41. Martin A., et al. “A Functional ABCC11 Allele Is Essential in the Biochemical Formation of Human Axillary Odor”. The Journal of Investigative Dermatolog2 (2010): 529-540.
42. James GA., et al. “Microbiological and biochemical origins of human axillary odor”. FEMS Microbiology Ecology 83 (2013): 527-540.
43. Ara K., et al. “Foot odor due to microbial metabolism and its control”. Canadian Journal of Microbiology4 (2006): 357-364.
44. Yamakoshi J., et al. “Effect of proanthocyanidin-rich extract from grape seeds on human fecal flora and fecal odor”. Microbial Ecology in Health and Disease 13 (2001): 25-31.
45. Tonzetich J. “Production and origin of oral malodor: a review of mechanisms and methods of analysis”. Journal of Periodontology1 (1977): 13-20.
46. Quirynen M., et al. “The impact of periodontal therapy and the adjunctive effect of antiseptics on breath odor-related outcome variables: a double-blind randomized study”. Journal of Periodontology5 (2005): 705-712.
47. Awano S., et al. “The relationship between the presence of periodontopathogenic bacteria in saliva and halitosis”. International Dental Journal3 (2002): 212-216.
48. Ramdurg P and Mendigeri V. “Halitosis: A review of etiology and management”. IOSR Journal of Dental and Medical Sciences4 (2014): 50-55.
49. Cortelli JR., et al. “Halitosis: a review of associated factors and therapeutic approach”. Brazilian Oral Research1 (2008).
50. Van Den Broek AM., et al. “A review of the current literature on management of halitosis”. Oral Diseases1 (2008): 30-39.
51. Yaegaki K and Coil JM. “Examination, Classification, and Treatment of Halitosis; Clinical Perspectives”. The Journal of the Canadian Dental Association 66 (2000): 257-261.
52. Quirynen M., et al. “Review of the treatment strategies for oral malodor”. The Journal Clinical Oral Investigations1 (2002): 1-10.
53. Goldberg S., et al. “Cadaverine as a putative component of oral malodor”. Journal of Dental Research6 (1994): 1168-1172.
54. Shinada K., et al. “A randomized, double blind, crossover, placebo-controlled clinical trial to assess the effects of a mouthwash containing chlorine dioxide on oral malodor”. Trials 9 (2008): 71.
55. Liu J., et al. “Cetylpyridinium chloride suppresses gene expression associated with halitosis”. Archives of Oral Biology11 (2013): 1686-1691.
56. Purba NAA. “Effectivity of kepel (Stelechocarpus burahol) fructus simplicia on reducing ammonia, trimethylamine, and phenol content in mice (Mus musculus) faecal”. Thesis, IPB Bogor (2011).