Research Article
Volume 8 Issue 9 - 2020
Metformin Used for Weight Loss by Non-Diabetic Sudanese Females
Abdelaziz SI1 and Miyada AM2
1Assistant Professor of Medicine, Consultant Internal Medicine and Endocrine, Soba University Hospital, University of Khartoum, Khartoum, Sudan
2Clinical Pharmacist, Mcs, Omdurman Islamic University, Omdurman, Sudan
*Corresponding Author: Abdelaziz SI, Assistant Professor of Medicine, Consultant Internal Medicine and Endocrine, Soba University Hospital, University of Khartoum, Khartoum, Sudan.
Received: April 04, 2020; Published: August 11, 2020




Abstract

Metformin, a principle Biguanide, is the main anti-diabetic agent for the treatment of T2DM. It reduces the insulin resistance associated with T2 DM. In addition, obesity, which is found to have a similar pathogenesis may be affected by treatment with Metformin. Young obese non-diabetic females have taken an interest in taking Metformin over-the-counter to lose weight.

Here we studied the practice of using Metformin for weight loss. We performed a cross-sectional study on 50 women, selected randomly at Khartoum State between November to December 2017. All of whom were females and 37.3% more than 30 years old. The majority had a BMI of 35 kg/m2.

Fifty-eight percent were not married, (28%) and (4%) were pharmacists and physicians respectively and 39.2% used only 500 mg of Metformin once a day. Ninety percent had abdominal disturbance, 58.8% stopped Metformin use because of side effects, 64.7% obtained metformin from the pharmacy as over the counter (OTC) medicines. Thirty percent obtained the information about metformin use from the social media or their friends, 58.8% observed weight loss by more than 5 kg. Fifty-four point nine percent and fifty-eight point eight percent had been on diet and exercise programs respectively, 64.7% were satisfied with their result. There were significant associations between weight reduction with, dose used, diet and exercise.

We conclude that women who used Metformin over the counter had a good experience with it especially when combined with diet and exercise.

Keywords: Metformin; Obesity; Weight Loss; Insulin Resistance

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Citation: Abdelaziz SI and Miyada AM. “Metformin Used for Weight Loss by Non-Diabetic Sudanese Females”. EC Pharmacology and Toxicology 8.9 (2020): 44-54.

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