Abstract

Cytidine 5-diphosphocholine (CDP-choline, or citicoline) is an indispensable intermediate in the biosynthesis of structural phospholipids in cell membranes, in particular phosphatidylcholine. The review is dedicated to the study of citicoline (Ceraxon). The experimental data on its effect on traumatic injury and experimental cerebral edema, as well as the results of clinical use in traumatic brain injury and its consequences, are highlighted.

Keywords: Citicoline; Acetylcholine; Traumatic Brain Injury; Cerebral Edema; Post-Traumatic Memory Impairment

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