Research Article
Volume 10 Issue 3 - 2021
Prognostic and Diagnostic Importance of IgG and IgM Antibodies in COVID-19
Syeda Huma H Zaidi1, Hayam A Elawamy2*, Sara Ali Sh Abdulla3, Rabha A El Sahly4, Abdul Hai5, Asaad Hasan Ansari6, Eman Z Younis7, Amithaba Basu8, Prajna Barke9, Rajesh Thangarajan10, FG Dawoodi11, Sunny Dawoodi12, Shakila Srikumar13, Vidhya Gunasakaran14 and Peela Jagannadha Rao15

1Department of Chemistry, Faculty of Science, Northern Border University, Arar, Saudi Arabia

2Department of Medical Laboratory, College of Medical Technology, Benghazi, Libya

3Department of Biochemistry, Faculty of Medicine, University of Benghazi, Benghazi, Libya

4Department of Internal Medicine (Neurology), Faculty of Medicine, Benghazi University, Benghazi, Libya

5Department of Biochemistry, Faculty of Applied Medical Sciences, Northern Border University, Arar, Saudi Arabia

6Schonberry Networks AB, Stockholm, Sweden

7Department of Biology, Faculty of Education, Ghemines University of Benghazi, Benghazi, Libya

8Dean and HOD, Department of Pathology, School of Medicine, St Matthews University, Grand Cayman, Cayman Islands

9Department of Physiology, St. Matthew’s University, School of Medicine, Grand Cayman, Cayman Islands

10Department of Histology, St. Matthew’s University, School of Medicine, Grand Cayman, Cayman Islands

11Department of Anesthesia, Faculty of Medicine, Quest International University Perak, Ipoh, Malaysia

12Department of Anesthesia, Raja Isteri Pengiran Anak Saleha (RIPAS) Hospital, Brunei Darussalam

13Department of Biochemistry, Melaka-Manipal Medical College (Manipal University), Jalan Padang Jambu, Bukit Baru, Melaka, Malaysia

14Department of Opthalmology, Hospital Selayang, Selayang, Malaysia

9Department of Medical Genetics, School of Medicine, St Matthews University, Grand Cayman, Cayman Islands

*Corresponding Author: Hayam A Elawamy, Department of Medical Laboratory, College of Medical Technology, Benghazi, Libya.
Received: February 07, 2021; Published: February 27, 2021




Abstract

COVID-19 infection is a novel disease caused by SARS-CoV-2. It emerged in December 2019 in China and spread rapidly causing a worldwide pandemic. Extensive research is underway globally to obtain more information regarding the pathogenesis, diagnosis and treatment of the novel disease. The diagnosis of COVID-19 infection is done by detection of SARS-CoV-2 viral RNA by polymerase chain reaction (PCR) technique or nucleic acid hybridization-related strategies and by detection of antibodies by serological and immunological assays. Reverse transcription polymerase chain reaction (RT PCR) and rapid antigen tests from a throat swab or nasopharyngeal swab are the most common modalities for the diagnosis of COVID-19 infection. Immunological testing involving estimation of IgG and IgM antibodies is gaining importance for the diagnosis of the disease. The aim of the present study is to evaluate the levels of immunoglobulins (IgM and IgG) in symptomatic and asymptomatic patients for the diagnosis and prognosis of COVID-19 infection.

 

Keywords Corona Virus 19 (COVID19); Immunoglobulin G (IgG); Immunoglobulin M (IgM); Prognostic and Diagnostic

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Citation: Hayam A Elawamy., et al. “Prognostic and Diagnostic Importance of IgG and IgM Antibodies in COVID-19 Patients- A Case Control Study”. EC Pulmonology and Respiratory Medicine 10.3 (2021): 87-91.

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