Mini Review
Volume 10 Issue 3 - 2021
COVID-19 So Much to Know - What about Two Old Drugs?
Wilhelm Grander*
University Teaching Hospital Hall in Tirol, Milserstrasse, Austria
*Corresponding Author: Wilhelm Grander, University Teaching Hospital Hall in Tirol, Milserstrasse, Austria.
Received: February 03, 2021; Published: February 16, 2021




Abstract

Through the modern information-technology the Covid-19 pandemic can be watched in real time by anybody. An enormous scientific information is teleported in the four walls of any physician’s home and office in an almost minute takt. Healthcare workers, doctors and nurses experienced how difficult it may be to filter the rapid cumulating information and adjusting it with daily praxis. Hospital physicians dealing with Covid-19 had to struggled at least with three intertwined, gradually changing phases: diagnosis, avoiding aerosolization and therapy - which got in the background of public observation because of the now ongoing politically dominated vaccination phase. However, Covid-19 is coined by two pathways - early viral replication and immune response syndrome which may lead into a cytokine storm syndrome the leading cause of death in this pandemic. Remdesivir which is indicated in the early phase has a modest effect on morbidity and very little on mortality. On contrary the anti-inflammatory drugs steroids and possibly colchicine, two old drugs seem to be gamechangers as direct therapies of SARS-CoV-2 infection.

Keywords: Covid-19; Vaccination Phase; SARS-CoV-2; Remdesivir

Citation: Wilhelm Grander. “COVID-19 So Much to Know - What about Two Old Drugs?”. EC Pulmonology and Respiratory Medicine 10.3 (2021): 38-41.

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