Research Article
Volume 7 Issue 8 - 2018
Analysis of the Sensitivity of Ultrasound-Guided Percutaneous Pleural Biopsies in the Diagnosis of Pleural Carcinomatosis and the Association between Parietal Pleural Thickness at Ultrasonography and Positive Result for Cancer. (Preliminary Results)
Fernanda Ayumi Fukuya1, Patrícia Mie Uwada1, Giovana Jatobá Guida1, Tamires Daiana da Silva Oliveira Virginio1, Igor Renato Louro Bruno de Abreu2* and Fernando Conrado Abrão3
1Undergraduate Medical Student, Universidade de Mogi das Cruzes, Mogi das Cruzes - SP, Brazil
2Assistant Physician, Thoracic Surgery Service, Hospital Santa Marcelina de Itaquera, São Paulo – SP, Brazil
3Physician, Coordinator of the Thoracic Surgery Service, Hospital Santa Marcelina de Itaquera, São Paulo – SP, Brazil
*Corresponding Author: Igor Renato Louro Bruno de Abreu, Assistant Physician, Thoracic Surgery Service, Hospital Santa Marcelina de Itaquera, São Paulo – SP, Brazil.
Received: June 21, 2018; Published: July 16, 2018
Citation: Igor Renato Louro Bruno de Abreu., et al. “Analysis of the Sensitivity of Ultrasound-Guided Percutaneous Pleural Biopsies in the Diagnosis of Pleural Carcinomatosis and the Association between Parietal Pleural Thickness at Ultrasonography and Positive Result for Cancer. (Preliminary Results)”. EC Pulmonology and Respiratory Medicine 7.8 (2018): 586-590.
Abstract
Introduction: Pleural biopsies performed through blind percutaneous punctures have low sensitivity in relation to surgical biopsies. In this context, a question is raised on how the association of imaging methods with the percutaneous puncture might increase the sensitivity of pleural needle biopsies in cases of carcinomatous pleuritis. To answer this question, the researchers developed a research protocol that compares ultrasound-guided pleural biopsies with pleural biopsies carried out by video-assisted thoracoscopy.
Objective: To present the partial results of the study aiming to evaluate the efficiency of ultrasound-guided pleural biopsy compared to the efficiency of pleural biopsy performed by video-assisted thoracoscopy, association between pleural thickness at the ultrasonography and the anatomopathological diagnosis of cancer infiltrating the parietal pleura.
Methods: The aim of the study is to evaluate 60 patients with pleural biopsy indication by video-assisted thoracoscopy. Participants will undergo a chest ultrasound examination to verify the maximum pleural thickness and ultrasound-guided. After, will undergo a second biopsy by video-assisted thoracoscopy. Both results will be compared, and a comparative analysis will be performed between a positive result for cancer and maximum pleural thickness measured by ultrasonography using the VassarStat online software.
Results: To date, 12 patients, 9 females, 3 males, have been assessed. In the analysis of positive result for neoplasia, when comparing the ultrasound-guided biopsy with the video-assisted biopsy, the odds ratio (OR) value was 0.4667, disclosing a greater chance of a positive diagnosis for cancer in surgical biopsies. However, a value of p = 0. Regarding pleural thickness, it was observed there was a greater chance of a cancer diagnosis in the group with greater pleural thickness, with an OR = 2 (95% CI: 0.082 to 2.6564); however, the sample size was not sufficient to guarantee statistical significance with p = 1.
Conclusion: The study shows there is a gain in sensitivity when ultrasound is associated with pleural puncture biopsy in comparison to a blind biopsy, but the method shows inferior results when compared to the surgical biopsy methods. There is a tendency for patients with greater parietal pleural thickness at the ultrasonography to show positive pleural biopsy results for cancer.
Keywords: Pleural Biopsy; Neoplastic Pleural Effusion; Pleural Neoplasia
Copyright: © 2018 Igor Renato Louro Bruno de Abreu., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

News and Events

Welcoming Article Submission

ECronicon delightfully welcomes the authors for submission of articles towards the upcoming issue of respective journals.

Submission Timeline

Last date for submission of articles is August 28, 2018.

Publication Certificate

Authors will be issued a "Publication Certificate" as a token of appreciation for publishing their work.

Best Article of the Issue

The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of "Best Article of the Issue".

Share this article

Visitors: 2845359