Case Report
Volume 9 Issue 9 - 2020
Early Stress and Harmful Use of Psychoactive Substances in Adult Life: Case Report
Fernando Kamimoto Eckmann Helene and César Augusto Trinta Weber*
Psychiatry Training Program, Jose de Barros Falcão Study Center, Porto Alegre, RS, Brazil
*Corresponding Author: César Augusto Trinta Weber, Medical Psychiatrist and Post-doctorate by the Department of Neuroscience and Behavioral Sciences at Ribeirão Preto Medical School, USP and Technical Director of the Clinical Psychiatry and Psychotherapy Clinic, Scientific Director, Supervisor and advisor of the Psychiatry Training Program at the Jose de Barros Falcão Study Center, Porto Alegre, RS, Brazil.
Received: May 10, 2020; Published: August 31, 2020


Introduction: Events as early stress may be able to alter the Central Nervous System through mechanisms such as gene-environment interaction, resulting in pathologies in adulthood.

Objective: Correlate early stress and its impact on the development of mental disorders associated with the harmful use of multiple psychoactive substances, risky behavior, and clinical comorbidity, such as alcoholic pancreatitis.

Methodology: A case report.

Results: In this study, the patient suffered physical, emotional, and sexual abuse, emotional neglect, in addition to the harmful use of alcohol and other psychoactive substances which generated alcoholic pancreatitis.

Conclusion: The early stress is intimal related to the gene expression, resulting in neuroendocrine changes, changes in the Immune System, and the stimulation of the Hypothalamic-Pituitary-Adrenal axis. These alterations result in neuro-structural changes, which can impact adult life.

Keywords: Physical Abuse; Substances Abuse; Early Stress; Mistreatment; Bipolar Disorder


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Citation: Fernando Kamimoto Eckmann Helene and César Augusto Trinta Weber. “Early Stress and Harmful Use of Psychoactive Substances in Adult Life: Case Report”. EC Psychology and Psychiatry 9.9 (2020): 61-65.

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