Research Article
Volume 9 Issue 7 - 2020
Gender Differences in Anxiety and Depression of Chronic Obstructive Pulmonary Disease Patients Submitted to Pulmonary Rehabilitation
Cecilia Melo Rosa Tavares*, Selma D Squassoni, Nadine C Machado, Julia Fiss, Elie Fiss and Monica S Lapa
Department of Pneumology Discipline, Centro Universitario Saude ABC, Brazil
*Corresponding Author: Cecilia Melo Rosa Tavares, Department of Pneumology Discipline, Centro Universitario Saude ABC, Brazil.
Received: April 27, 2020; Published: June 18, 2020




Abstract

Objective: To compare the benefits of Pulmonary Rehabilitation Program (PRP) between men and women with COPD regarding levels of anxiety and depression, quality of life and physical performance.

Design: Nonrandomized controlled trial. Patients were assessed by Saint George´s Respiratory Questionnaire (SRQG), the six-minute walk test(6MWT), the Beck Anxiety Inventory (BAI) and the Beck Depression Inventory (BDI) before (pre-PRP) and three months after (post-PRP) PRP.

Setting: Pulmonary Rehabilitation Center.

Participants: Thirty-three patients were evaluated pre-PRP and post-PRP. Five of thirty-eight patients were excluded because they found it difficult to attend the sessions.

Interventions: Pulmonary Rehabilitation Program (PRP).

Main Outcome Measure(s): Men improved their depression and anxiety. Women improved their quality of life and both genders performed better in the 6MWT.

Results: Men patients improved their depression score (BDI: pre-PRP: 19.6 ± 9.2, post-PRP: 15.3 ± 9.3, p < 0.05), decreased their anxiety score (PRP-pre: 15.9 ± 12.8, post-PRP: 11.8 ± 10.1, p < 0.05) and didn´t improve the quality of life after PRP. Women showed no improvement on their depression (pre-PRP: 20.3 ± 8.9, post-PRP: 18 ± 8.1, p ≥ 0.05) and anxiety (pre-PRP: 15.2 ± 11.6, post-PRP: 12.9 ± 13.1, p ≥ 0.05), but improved their quality of life (pre-PRP: 33,2 ± 12; post-PRP: 20.3 ± 12.6, p < 0.05). Both genders improved their performance in the 6MWT (Men: pre-PRP: 349 ± 101.4m, post-PRP: 379.7 ± 87.1m, p < 0.05; Women: pre-PRP: 361.8 ± .85.9, post -PRP: 390.5 ± 61.5, p < 0.05).

Conclusion: This study indicates that men and women respond differently to the PRP.

Keywords: Chronic Obstructive Pulmonary Disease; Anxiety; Depression; Quality of Life; Pulmonary Rehabilitation

References

  1. Soriano JB., et al. “Recent trends in physician diagnosed COPD in women and men in the UK”. Thorax 9 (2000): 789-794.
  2. Carrasco-Garrido P., et al. “Characteristics of chronic obstructive pulmonary disease in Spain from a gender perspective”. BMC Pulmonary Medicine1 (2009): 2.
  3. Aryal S., et al. “COPD and gender differences: an update”. Translational Research4 (2013): 208-218.
  4. de Torres JP., et al. “Gender and COPD in patients attending a pulmonary clinic”. Chest4 (2005): 2012-2016.
  5. Maurer J., et al. “Anxiety and depression in COPD: current understanding, unanswered questions, and research needs”. Chest 4 (2008): 43S-56S.
  6. Di Marco F., et al. “Anxiety and depression in COPD patients: the roles of gender and disease severity”. Respiratory Medicine10 (2006): 1767-1774.
  7. de Torres Tajes JP and Macario CC. “EPOC en la mujer”. Archivos de Bronconeumología 46 (2010): 23-27.
  8. Godoy RFd., et al. “Repercussões tardias de um programa de reabilitação pulmonar sobre os índices de ansiedade, depressão, qualidade de vida e desempenho físico em portadores de DPOC”. Jornal Brasileiro de Pneumologia2 (2009): 129-136.
  9. Spielmanns M., et al. “Effects on pulmonary rehabilitation in patients with COPD or ILD: a retrospective analysis of clinical and functional predictors with particular emphasis on gender”. Respiratory Medicine 113 (2016): 8-14.
  10. de Sousa TC., et al. “Validação do Questionário do Hospital Saint George na Doença Respiratória (SGRQ) em pacientes portadores de doença pulmonar obstrutiva crônica no Brasil”. Jornal Brasileiro de Pneumologia3 (2000): 119-128.
  11. Machado NC., et al. “Estudo comparativo entre os resultados do teste de caminhada de seis minutos e do teste do degrau de seis minutos em pacientes com Doença Pulmonar Obstrutiva Crônica”. Arquivos Médicos do ABC2 (2007).
  12. Nici L., et al. “American thoracic society/European respiratory society statement on pulmonary rehabilitation”. American Journal of Respiratory and Critical Care Medicine12 (2006): 1390-1413.
  13. Troosters T., et al. “Pulmonary rehabilitation in chronic obstructive pulmonary disease”. American Journal of Respiratory and Critical Care Medicine1 (2005): 19-38.
  14. Vogelmeier CF., et al. “Global strategy for the diagnosis, management, and prevention of chronic obstructive lung disease 2017 report. GOLD executive summary”. American Journal of Respiratory and Critical Care Medicine5 (2017): 557-582.
  15. Cully JA., et al. “Quality of life in patients with chronic obstructive pulmonary disease and comorbid anxiety or depression”. Psychosomatics4 (2006): 312-319.
  16. McCathie HCF., et al. “Adjustment to chronic obstructive pulmonary disease: the importance of psychological factors”. European Respiratory Journal1 (2002): 47-53.
  17. Emery CF., et al. “Psychological outcomes of a pulmonary rehabilitation program”. Chest 3 (1991): 613-617.
  18. Güell R., et al. “Impact of pulmonary rehabilitation on psychosocial morbidity in patients with severe COPD”. Chest 4 (2006): 899-904.
  19. Kunik ME., et al. “Surprisingly high prevalence of anxiety and depression in chronic breathing disorders”. Chest 4 (2005): 1205-1211.
  20. Hynninen MJ., et al. “Factors affecting health status in COPD patients with co-morbid anxiety or depression”. International Journal of Chronic Obstructive Pulmonary Disease3 (2007): 323-328.
  21. Naberan K., et al. “Impairment of quality of life in women with chronic obstructive pulmonary disease”. Respiratory Medicine3 (2012): 367-373.
  22. Rodríguez-Pecci MS., et al. “Enfermedad pulmonar obstructiva: diferencias entre hombres y mujeres”. Medicina (Buenos Aires) 3 (2012): 207-215.
  23. DE Voogd Jacob N., et al. “Relationship between anxiety and dyspnea on exertion in patients with chronic obstructive pulmonary disease”. Anxiety, Stress and Coping 4 (2011): 439-449.
  24. Janssens Thomas., et al. “Dyspnea perception in COPD: association between anxiety, dyspnea-related fear, and dyspnea in a pulmonary rehabilitation program”. Chest 3 (2011): 618-625.
  25. Robles PG., et al. “Gender-associated differences in pulmonary rehabilitation outcomes in people with chronic obstructive pulmonary disease: a systematic review”. Journal of Cardiopulmonary Rehabilitation and Prevention2 (2014): 87-97.
  26. Da Costa CC., et al. “Effect of a Pulmonary Rehabilitation Program on the levels of anxiety and depression and on the quality of life of patients with chronic obstructive pulmonary disease”. Revista Portuguesa de Pneumologia (English Edition)6 (2014): 299-304.
  27. Pneumol I. “Redução nos níveis de ansiedade e depressão de pacientes com doença pulmonar obstrutiva crônica (DPOC) participantes de um programa de reabilitação pulmonar”. Jornal Brasileiro de Pneumologia3 (2002): 120.
Citation: Cecilia Melo Rosa Tavares., et al. “Gender Differences in Anxiety and Depression of Chronic Obstructive Pulmonary Disease Patients Submitted to Pulmonary Rehabilitation”. EC Psychology and Psychiatry 9.7 (2020): 53-60.

PubMed Indexed Article


EC Pharmacology and Toxicology
LC-UV-MS and MS/MS Characterize Glutathione Reactivity with Different Isomers (2,2' and 2,4' vs. 4,4') of Methylene Diphenyl-Diisocyanate.

PMID: 31143884 [PubMed]

PMCID: PMC6536005


EC Pharmacology and Toxicology
Alzheimer's Pathogenesis, Metal-Mediated Redox Stress, and Potential Nanotheranostics.

PMID: 31565701 [PubMed]

PMCID: PMC6764777


EC Neurology
Differences in Rate of Cognitive Decline and Caregiver Burden between Alzheimer's Disease and Vascular Dementia: a Retrospective Study.

PMID: 27747317 [PubMed]

PMCID: PMC5065347


EC Pharmacology and Toxicology
Will Blockchain Technology Transform Healthcare and Biomedical Sciences?

PMID: 31460519 [PubMed]

PMCID: PMC6711478


EC Pharmacology and Toxicology
Is it a Prime Time for AI-powered Virtual Drug Screening?

PMID: 30215059 [PubMed]

PMCID: PMC6133253


EC Psychology and Psychiatry
Analysis of Evidence for the Combination of Pro-dopamine Regulator (KB220PAM) and Naltrexone to Prevent Opioid Use Disorder Relapse.

PMID: 30417173 [PubMed]

PMCID: PMC6226033


EC Anaesthesia
Arrest Under Anesthesia - What was the Culprit? A Case Report.

PMID: 30264037 [PubMed]

PMCID: PMC6155992


EC Orthopaedics
Distraction Implantation. A New Technique in Total Joint Arthroplasty and Direct Skeletal Attachment.

PMID: 30198026 [PubMed]

PMCID: PMC6124505


EC Pulmonology and Respiratory Medicine
Prevalence and factors associated with self-reported chronic obstructive pulmonary disease among adults aged 40-79: the National Health and Nutrition Examination Survey (NHANES) 2007-2012.

PMID: 30294723 [PubMed]

PMCID: PMC6169793


EC Dental Science
Important Dental Fiber-Reinforced Composite Molding Compound Breakthroughs

PMID: 29285526 [PubMed]

PMCID: PMC5743211


EC Microbiology
Prevalence of Intestinal Parasites Among HIV Infected and HIV Uninfected Patients Treated at the 1o De Maio Health Centre in Maputo, Mozambique

PMID: 29911204 [PubMed]

PMCID: PMC5999047


EC Microbiology
Macrophages and the Viral Dissemination Super Highway

PMID: 26949751 [PubMed]

PMCID: PMC4774560


EC Microbiology
The Microbiome, Antibiotics, and Health of the Pediatric Population.

PMID: 27390782 [PubMed]

PMCID: PMC4933318


EC Microbiology
Reactive Oxygen Species in HIV Infection

PMID: 28580453 [PubMed]

PMCID: PMC5450819


EC Microbiology
A Review of the CD4 T Cell Contribution to Lung Infection, Inflammation and Repair with a Focus on Wheeze and Asthma in the Pediatric Population

PMID: 26280024 [PubMed]

PMCID: PMC4533840


EC Neurology
Identifying Key Symptoms Differentiating Myalgic Encephalomyelitis and Chronic Fatigue Syndrome from Multiple Sclerosis

PMID: 28066845 [PubMed]

PMCID: PMC5214344


EC Pharmacology and Toxicology
Paradigm Shift is the Normal State of Pharmacology

PMID: 28936490 [PubMed]

PMCID: PMC5604476


EC Neurology
Examining those Meeting IOM Criteria Versus IOM Plus Fibromyalgia

PMID: 28713879 [PubMed]

PMCID: PMC5510658


EC Neurology
Unilateral Frontosphenoid Craniosynostosis: Case Report and a Review of the Literature

PMID: 28133641 [PubMed]

PMCID: PMC5267489


EC Ophthalmology
OCT-Angiography for Non-Invasive Monitoring of Neuronal and Vascular Structure in Mouse Retina: Implication for Characterization of Retinal Neurovascular Coupling

PMID: 29333536 [PubMed]

PMCID: PMC5766278


EC Neurology
Longer Duration of Downslope Treadmill Walking Induces Depression of H-Reflexes Measured during Standing and Walking.

PMID: 31032493 [PubMed]

PMCID: PMC6483108


EC Microbiology
Onchocerciasis in Mozambique: An Unknown Condition for Health Professionals.

PMID: 30957099 [PubMed]

PMCID: PMC6448571


EC Nutrition
Food Insecurity among Households with and without Podoconiosis in East and West Gojjam, Ethiopia.

PMID: 30101228 [PubMed]

PMCID: PMC6086333


EC Ophthalmology
REVIEW. +2 to +3 D. Reading Glasses to Prevent Myopia.

PMID: 31080964 [PubMed]

PMCID: PMC6508883


EC Gynaecology
Biomechanical Mapping of the Female Pelvic Floor: Uterine Prolapse Versus Normal Conditions.

PMID: 31093608 [PubMed]

PMCID: PMC6513001


EC Dental Science
Fiber-Reinforced Composites: A Breakthrough in Practical Clinical Applications with Advanced Wear Resistance for Dental Materials.

PMID: 31552397 [PubMed]

PMCID: PMC6758937


EC Microbiology
Neurocysticercosis in Child Bearing Women: An Overlooked Condition in Mozambique and a Potentially Missed Diagnosis in Women Presenting with Eclampsia.

PMID: 31681909 [PubMed]

PMCID: PMC6824723


EC Microbiology
Molecular Detection of Leptospira spp. in Rodents Trapped in the Mozambique Island City, Nampula Province, Mozambique.

PMID: 31681910 [PubMed]

PMCID: PMC6824726


EC Neurology
Endoplasmic Reticulum-Mitochondrial Cross-Talk in Neurodegenerative and Eye Diseases.

PMID: 31528859 [PubMed]

PMCID: PMC6746603


EC Psychology and Psychiatry
Can Chronic Consumption of Caffeine by Increasing D2/D3 Receptors Offer Benefit to Carriers of the DRD2 A1 Allele in Cocaine Abuse?

PMID: 31276119 [PubMed]

PMCID: PMC6604646


EC Anaesthesia
Real Time Locating Systems and sustainability of Perioperative Efficiency of Anesthesiologists.

PMID: 31406965 [PubMed]

PMCID: PMC6690616


EC Pharmacology and Toxicology
A Pilot STEM Curriculum Designed to Teach High School Students Concepts in Biochemical Engineering and Pharmacology.

PMID: 31517314 [PubMed]

PMCID: PMC6741290


EC Pharmacology and Toxicology
Toxic Mechanisms Underlying Motor Activity Changes Induced by a Mixture of Lead, Arsenic and Manganese.

PMID: 31633124 [PubMed]

PMCID: PMC6800226


EC Neurology
Research Volunteers' Attitudes Toward Chronic Fatigue Syndrome and Myalgic Encephalomyelitis.

PMID: 29662969 [PubMed]

PMCID: PMC5898812


EC Pharmacology and Toxicology
Hyperbaric Oxygen Therapy for Alzheimer's Disease.

PMID: 30215058 [PubMed]

PMCID: PMC6133268


News and Events


July Issue Release

We always feel pleasure to share our updates with you all. Here, notifying you that we have successfully released the July issue of respective journals and can be viewed in the current issue pages.

Submission Deadline for August Issue

Ecronicon delightfully welcomes all the authors around the globe for effective collaboration with an article submission for the August issue of respective journals. Submissions are accepted on/before July 21, 2020.

Certificate of Publication

Ecronicon honors with a "Publication Certificate" to the corresponding author by including the names of co-authors as a token of appreciation for publishing the work with our respective journals.

Best Article of the Issue

Editors of respective journals will always be very much interested in electing one Best Article after each issue release. The authors of the selected article will be honored with a "Best Article of the Issue" certificate.

Certifying for Review

Ecronicon certifies the Editors for their first review done towards the assigned article of the respective journals.

Latest Articles

The latest articles will be updated immediately on the articles in press page of the respective journals.

Immediate Assistance

The prime motto of this team is to clarify all the queries without any delay or hesitation to avoid the inconvenience. For immediate assistance on your queries please don't hesitate to drop an email to editor@ecronicon.uk