Research Article
Volume 9 Issue 3 - 2020
Fatigue Assessment during Breast Cancer Radiotherapy
Hanene Ben Salah* and Jamel Daoud
Department of Radiotherapy, Habib Bourguiba Hospital and University Center Sfax, Tunisia
*Corresponding Author: Hanene Ben Salah, Department of Radiotherapy, Habib Bourguiba Hospital and University Center Sfax, Tunisia.
Received: January 06, 2020; Published: February 24, 2020




Abstract

Objective: The objective of this work is to assess fatigue and its impact on the daily life of patients undergoing post-operative radiotherapy for breast cancer.

Patients and Methods: Fatigue was assessed during radiotherapy in patients treated for non-metastatic breast cancer, at the radiotherapy department of the Habib Bourguiba University Hospital in Sfax, Tunisia. The validated Arabic version of the "Multidimentionnal fatigue Inventory" was used. Fatigue assessment was also done in a group of witnesses. 

Results: 50 patients of average age 50 were included, 77 witnesses of average age 45 responded to the questionnaire. All the patients described a feeling of fatigue with variable score. The total fatigue score was 27 to 81 and an average of 51.32. The means of the scores of the different dimensions of fatigue were 10.22 for general fatigue, 11.22 for physical fatigue, 10.78 for reduced activity, 8.5 for reduced motivation and 10.6 for mental fatigue. The number of patients with a total score greater than or equal to 50 was 21 (42%). These scores were lower than those of the witnesses group, and higher than those of the workers of witnesses group.

Conclusion: During radiotherapy for breast cancer patients have a high fatigue score which predominates in the physical and mental dimension while the motivation is not altered. To attribute this fatigue to radiation, other studies are needed to assess fatigue before, during and after radiotherapy, possibly in different institutions with a standardization of the means of evaluation.

Keywords:Fatigue; Breast Cancer; Radiotherapy

References

  1. Smets EM., et al. “Fatigue in cancer patients”. British Journal of Cancer 68 (1993): 220.
  2. Dilhuydy JM., et al. “Fatigue et radiothérapie Revue de la littérature”. Cancer/Radiothérapie 5 (2001): 131s-138s.
  3. Radbruch L., et al. “Fatigue in palliative care patients an EAPC approach”. Palliative Medicine 22 (2008): 13-32.
  4. Menezes Mde F and Camargo TC. “Cancer-related fatigue as a thematic issue in oncology nursing”. Revista Latino-Americana de Enfermagem 14 (2006): 442-447.
  5. Servaes P., et al. “Relations between fatigue, neuropsychological functioning, and physical activity after treatment for breast carcinoma: daily self-report and objective behavior”. Cancer 95 (2002): 2017-2026.
  6. Wafaa H and Hanaa S. “The Arabic Version of Multidimensional Fatigue Inventory: Reliability, Validity and Findings in Three Groups”. The Egyptian Journal of Psychiatry 20 (1997): 1.
  7. Kochbati L., et al. “Fatigue liée au cancer: Un symptôme souvent négligé”. Cancer/Radiothérapie 15 (2011): 605.
  8. Jereczek-Fossa BA., et al. “Radiotherapy-related fatigue”. Critical Reviews in Oncology/Hematology 41 (2002): 317-325.
  9. Muszalik M., et al. “Quality of life of women with breast cancer undergoing radiotherapy using the Functional Assessment of Chronic Illness Therapy-Fatigue questionnaire”. Clinical Interventions in Aging 11 (2016): 1489-1494.
  10. Ben Salah H., et al. “Ya t il une fatigue liée à la radiothérapie du cancer du sein?”. Cancer/Radiothérapie 20 (2016): 721.  
  11. Greenberg DB., et al. “Fatigue syndrome due to localized radiation”. Journal of Pain and Symptom Management 7 (1992): 38-45.
  12. Smets EM., et al. “Application of the multidimensional fatigue inventory (MFI-20) in cancer patients receiving radiotherapy”. British Journal of Cancer 73 (1996): 241.
  13. Smets EM., et al. “Fatigue and radiotherapy: (A) experience in patients undergoing treatment”. British Journal of Cancer 78 (1998): 899-906.
  14. Smets EM., et al. “Fatigue and radiotherapy: (B) experience in patients 9 months following treatment”. British Journal of Cancer 78 (1998): 907-912. 
  15. TR de M Alcantara-Silva., et al. “Fatigue related to radiotherapy for breast and/or gynaecological cancer : a systematic review”. Journal of Clinical Nursing 22 (2013): 2679-2686.
  16. Geinitz H., et al. “Fatigue, serum cytokine levels, and blood cell counts during radiotherapy of patients with breast cancer”. International Journal of Radiation Oncology, Biology, Physics 51.3 (2001): 691-698. 
  17. Geinitz H., et al. “Fatigue in patients with adjuvant radiation therapy for breast cancer: long-term follow-up”. Journal of Cancer Research Clinical Oncology 130 (2004): 327-333. 
  18. Wratten C., et al. “Fatigue during breast radiotherapy and its relationship to Biological factors”. International Journal of Radiation Oncology, Biology, Physics 59 (2004): 160-167.
  19. Lavdaniti M., et al. “Prospective Assessment of Fatigue and Health Status in Greek Patients with Breast Cancer Undergoing Adjuvant Radiotherapy”. Oncology Nursing Forum 33 (2006): 603-609.
  20. Moadel AB., et al. “Randomized Controlled Trial of Yoga Among a Multiethnic Sample of Breast Cancer Patients : Effects on Quality of Life”. Journal of Clinical Oncology 28 (2007): 4386-4395.
  21. Hwang JH., et al. “Effects of Supervised Exercise Therapy in Patients Receiving Radiotherapy for Breast Cancer”. Yonsei Medical Journal 49 (2008): 443-450.
  22. Lee TS., et al. “Quality of life of women treated with radiotherapy for breast cancer”. Support Care Cancer 16 (2008): 399-405.
  23. Montgomery GH., et al. “Fatigue during breast cancer radiotherapy : an initial randomized study of cognitive-behavioral therapy plus hypnosis”. Health Psychology Journal 28 (2009): 317-322.
  24. Cramp F and Daniel J. “Exercise for the management of cancer-related fatigue in adults”. Cochrane database of Systematic Reviews 2 (2008): CD006145 .
  25. Tarrasch R., et al. “The Effect of Reflexology on the Pain-Insomnia-Fatigue disturbance Cluster of Breast Cancer Patients During Adjuvant Radiation Therapy”. The Journal of Alternative and Complementary Medicine (2017): 1-7.
  26. Pan YQ., et al. “Massage interventions and treatment-related side effects of breast cancer : A systematic review and meta-analysis”. International Journal of Clinical Oncology 19 (2014): 829-841.
  27. Alcântara-Silva TR., et al. “Music Therapy Reduces Radiotherapy-Induced Fatigue in Patients with Breast or Gynecological Cancer: A Randomized Trial”. Integrative Cancer Therapies 1 (2018): 1-8.
Citation: Hanene Ben Salah and Jamel Daoud. “Fatigue Assessment during Breast Cancer Radiotherapy”. EC Psychology and Psychiatry 9.3 (2020): 01-11.

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