Review Article
Volume 11 Issue 4 - 2022
Perspectives in COVID-19 Vaccines for Children
Suraj Gupte1*, Novy Gupte2 and Sushmita Patil3
1Professor and Head (Emeritus), Postgraduate Department of Paediatrics, NMC and General and Superspeciality Hospitals, Khammam, Telangana, India
2Assistant Professor, Department of Pharmacology, Army Medical College, New Delhi, India
3Consultant Paediatrician, Wadia Hospital, Mumbai, India
*Corresponding Author: Suraj Gupte, Professor and Head (Emeritus), Postgraduate Department of Paediatrics, NMC, Khammam, Telangana, India.
Received: December 01, 2021; Published: March 30, 2022


Background: A large proportion of the adult population has already received vaccine against the COVID-19. On account of issues related to availability of the vaccines and safety restraints, the child population, comprising around one-third of the world population, stands more or less left out.

Objective: Developing a state-of-the-art update on different aspects of COVID-19 vaccination of children and the vaccines that are now available for actual use.

Design: Review of the English medical literature concerning COVID-19 vaccination of children with special reference to the vaccines that have become available for administration to paediatric population.

Salient Features: COVID-19 pandemic has so far been defying availability of a specific medication against the causative virus. Mercifully, scientists have done a spectacular job in developing a number of vaccines in less than a year after the identification of the aetiological virus. The vaccines are being extensively used worldwide to vaccinate the adult population. The approval of vaccines, successfully tested for children, has come only recently. Hence, the use has just got off the ground in restricted age groups and is picking up.

Conclusion: Like adults, virtually all children must be vaccinated against COVID-19. However, vaccination of children against COVID- 19 is a recent development. Presently, Pfizer-BioNTech and Chinese Sinovac vaccines are available for use. Indian Covaxin has now been included in the national campaign for children aged 12-17 years. Moderna vaccine for children > 12 years is also approved. It is felt that child vaccination against COVID-19 must pick up. Else, the gains from adult vaccination may well be diluted since unvaccinated children are likely to spread the virus widely and a proportion may suffer from severe complications, including the multisystem inflammatory system (MIS-C).

Keywords: Children; COVID-19 Vaccines; MIS-C; Pfizer-BioNTech Vaccine; Sinovac’s Vaccine


  1. Novy Gupte and Sapna Pradhan. “Vaccines: Issues and concerns”. EC Pharmacology and Toxicology2 (2021): 1-2.
  2. D Cucinotta and Vanelli M. “WHO declares COVID-19 a pandemic”. Acta Biomedica1 (2020): 157-160.
  3. A Harrison. “A global crisis”. In: Harrison A, Lucy ME, eds. COVID-19: Issues and Controversies. Philadelphia: United Publishers (2021): 121-129.
  4. ME Lucy. “Fighting the disastrous situation”. In: Harrison A, Lucy ME, eds. COVID-19: Issues and Controversies. Philadelphia: United Publishers (2021): 154-159.
  5. Suraj Gupte and Novy Gupte. “Antimicrobial resistance: Prevention and control”. American Journal of Medicine and Public Health 3 (2021): 1621-1625.
  6. “Covid: New variant classes of concern and named Omicron” (2021).
  7. Ministry of Health and Family Welfare, Government of India. COVID-19 Vaccination as on : 26 March 2022 (2022).
  8. World Health Organisation. “WHO validates SinoVac COPVID vaccine for emergency use and issues interim policy recommendations” (2021).
  9. A Shet. “COVID-19 vaccines in children. Road map for a safer world” (2021).
  10. L Gaddes. “Are COVID-19 vaccines safe for adolescents and children” (2021).
  11. Centre for Disease Control and Prevention. “COVID-19 vaccines for children and teens” (2021).
  12. W Kufel. “When can children get COVID-19 vaccine” (2021).
  13. Suraj Gupte S. “Annotation: “COVID-19 and children: What about the vaccine?””. Asian Bulletin of Infectious Diseases 2 (2021): 124-125.
Citation: Suraj Gupte., et al. “Perspectives in COVID-19 Vaccines for Children”. EC Paediatrics 11.4 (2022): 74-77.

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