Case Report
Volume 9 Issue 9 - 2020
Kawasaki’s Disease: About an Unusual Case
Karima El Fakiri*, G Draiss, N Rada and M Bouskraoui
Kawasaki’s Disease: About an Unusual Case
*Corresponding Author: Karima El Fakiri, Pediatric Unit A Hospital Mother and Child, University Hospital Mohammed VI, Marrakech, Morocco.
Received: July 16, 2020; Published: July 31, 2020


Kawasaki disease is the second most common vasculitis in children after rheumatoid purpura. We report a case of a 7-year-old boy with typical Kawasaki disease occlusive syndrome and coronary artery disease. Echocardiography shows a giant aneurysm of the left coronary artery of 9 mm and the right coronary artery 7 mm. This observation highlights the interest of not disregarding kawasaki’s disease in front of all its complete incomplete or atypical forms to delay the diagnosis and the treatment. It emphasizes the importance of giving immunoglobulins as early as possible to prevent coronary involvement.

Keywords: Kawasaki; Child; Aneurism; Occlusive Syndrome; Immunoglobulins


  1. NakamuraY and Yanagawa H. “The worldwide epidemiology of Kawasaki disease”. Progress in Pediatric Cardiology 19 (2004): 99-108.
  2. Chantepie A. “Kawasaki disease: when to seek the advice of the cardiopediatrician?” Pediatric Realities 148 (2010): 1-6.
  3. Mouko A., et al. “Kawasaki syndrome: about two cases observed in brazaville”. Bulletin de la Société de Pathologie Exotique 94.2 (2001): 109-111.
  4. Mahdhaoui A., et al. “Cardiovascular manifestations of Kawasaki syndrome: Contribution of cardiography in diagnosis and evolution”. Journal Medical Tunisie 81 (2003): 879-884.
  5. Bourillon A. “Kawasaki disease in all its facets”. Pediatrics Archives 15.5 (2008): 825-828.
  6. Bressieux-degueldre S., et al. “Kawasaki disease: update”. Revue Médicale Suisse 14 (2018): 384-389.
  7. Newburger JW., et al. “Diagnosis, treatment and long-term management of Kawasaki disease: a statement for health professionals from the committee on rheumatic fever, endocarditis, and Kawasaki disease, Council on Cardiovascular Disease in the Young, American Heart Association”. Pediatrics 114 (2004): 1708-1733.
  8. Bader-Meunier B. “Kawasaki disease: watch out for atypical form”. Childhood Medicine 6 (2003): 343-347. 
  9. Galeotti C., et al. “Kawasaki disease: A etiopathogenesis and therapeutic utility of intravenous immunoglobulin”. Autoimmunity Reviews 9 (2010): 441-448.
  10. Ozen S., et al. “Eular /Pres endorsed consensus criteria for the classification of childhood vasculitides”. Annals of the Rheumatic Diseases 65 (2006): 936-941.
  11. Wood LE and Tulloh RMR. “Diagnosis and management of Kawasaki disease in children”. Paediatrics and Child Health 18 (2007): 70-74.
  12. Yilmazer MM., et al. “Incomplete (atypical) Kawasaki disease in a young infant with remarkable paucity of signs”. Rheumatology International 30 (2010): 991-992.
  13. Cimaz R., et al. “Atypical and incomplete Kawasaki disease”. Best Practice and Research: Clinical Rheumatology 23 (2009): 689-697.
  14. Kato H., et al. “Fate of coronary rate of kawasaki disease: serial coronary angiography and long term follow- up”. The American Journal of Cardiology 49 (1984): 1758-1766.
  15. Bader-Meunier B., et al. “Cardiac complications of Kawasaki disease”. Parisian pediatrics. Flammarion medecine sciences. 
  16. Gerding R. “Kawasaki disease: A review”. Journal of Pediatric Health Care 25 (2011): 379-387.
  17. Gaudelus J., et al. “Kawasaki syndrome in France: 5 year retrospective survey”. Médecine et Maladies Infectieuses 10.2 (1998): 542-548.
  18. Grimpel E., et al. “Cardial complications of Kawasaki disease: retrospective study carried out at trousseau hospital 1987- 1993. About 38 cases. Parisian pediatrics”. Ed Flam Méd Sc Paris (1995): 151-158.
  19. Zulian F., et al. “Acute surgical abdomen as presenting manifestation of Kawasaki disease”. The Journal of Pediatrics 42.6 (2003): 731-735.
  20. Colomba C., et al. “Intestinal involvement in kawasaki disease”. The Journal of Pediatrics 220 (2018): 186-193.
  21. Leung DY. “Kawasaki disease”. Current Opinion in Rheumatology 5 (1993): 41- 50. 
  22. Sakulchit T., et al. “Acetylsalisilic acid for children with kawasaki disease”. The Canadian Family Doctor 63 (2017): 359-362.
  23. Tse SML., et al. “Early treatment with intravenous immunoglobulin in patients with Kawasaki disease”. The Journal of Pediatrics 140 (2002): 450-455.
  24. Cimaz R and Lega JC. “Kawasaki disease”. The Practitioner S Review 57 (2007): 1985-1988.
  25. Chantepie A., et al. “Cardiovascular complications of kawasaki syndrome: results of a French multi-center cardiopediatric survey”. Arch of Pediatrics 8 (2001): 713-719.
  26. Bajolle F. “Kawasaki disease”. EMC-Angeiology 7.1 (2012): 19-1800.
Citation: Karima El Fakiri., et al. “Kawasaki’s Disease: About an Unusual Case”. EC Paediatrics 9.8 (2020): 55-60.

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