Case Series
Volume 9 Issue 6 - 2020
Cases of Neuroborreliosis in Children of the Ternopil Region
Svitlana Nykytyuk1*, SI Klymnyuk1 and MM Kostyk2
1Ternopil National Medical University I. Horbachevskyi, Ukraine
2Ternopil Regional Children's Clinical Hospital, Ukraine
*Corresponding Author: Svitlana Nykytyuk, Ternopil National Medical University I. Horbachevskyi, Ukraine.
Received: April 12, 2020; Published: May 20, 2020




Abstract

Background: Neuroborreliosis is the most common manifestation of the disseminated form of Lyme disease features of central and peripheral nervous system involvement.

Materials and Methods: We reviewed charts of 95 patients with diagnosis of encephalitis. Among them we identified 7 of patients with neuroborreliosis (NB). Diagnosis of NB was made based on history, physical examination, laboratory data (positive anti-borrelia IgM on ELISA with immunoblot confirmation as well as abnormalities on MRI of the brain that were attributed to infectious process (Neuro-Lyme). A case of neuroborreliosis in a children is presented.

Results: The peculiarity of the presented case is in 3 children was diagnosed co-infection with tick-born encephalitis, granulocytic anaplasmosis and herpes virus infection. At an early stage, neurological symptoms occur up to 6 months after the tick bite and in a late stage of borreliosis - after more than 6 months.

Conclusion: 1. For differential diagnosis of neuroinfections and Lyme neuroborreliosis, it is necessary to observe two-stage serological investigation of blood, especially use of antibody screening tests by ELISA with subsequent confirmation by the Western blot assay. 2. Taking into account the ambiguity of approaches in the treatment of the examined group of children in Ukraine, treatment of neuroinfection requires standardization of treatment protocols in accordance with the requirements of the World Health Organization. 3. The course of the disease may different from the classical triad and includes only cerebrospinal syndrome or cervical myalgia. 4. Possibility of co-infections with herpes virus, anaplasma can be present in the patients, proper care must be taken to recognize and treat them.

Keywords: Child; Borrelia burgdorferi; Lyme Disease; Neuroborreliosis; Human Granulocytic Anaplasmosis; ELISA; Western-blot; IgM; IgG

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Citation: Svitlana Nykytyuk., et al. “Cases of Neuroborreliosis in Children of the Ternopil Region”. EC Paediatrics 9.6 (2020): 93-102.

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