Research Article
Volume 9 Issue 6 - 2020
Anaemia among Female Undergraduate Students of Usmanu Danfodiyo University Sokoto, Nigeria.
Erhabor Osaro1*, Halima Aliyu Gada1, Mgbere Osaro2 and Erhabor Tosan3
1School of Medical Laboratory Science Usmanu Danfodiyo University Sokoto, Nigeria
2Institute of Community Health (ICH); Department of Pharmaceutical Health Outcomes and Policy, University of Houston College of Pharmacy, Houston, Texas, USA
3Medical Laboratory Science Council of Nigeria, Nigeria
*Corresponding Author: Erhabor Osaro, School of Medical Laboratory Science Usmanu Danfodiyo University Sokoto, Nigeria.
Received: April 13, 2020; Published: May 18, 2020




Abstract

Introduction: Anaemia is a major public health problem affecting a significant number of the world's population.

Objectives:This case study was performed on seventy-two (72) female undergraduates’ students of the Usmanu Danfodiyo University, Sokoto , Nigeria with a mean age 22.38 ± 1.98 years with the aim of determing the prevalence and etiological factors responsible for anaemia among the study population.

Methods: Five millimeters of blood of blood were collected from each subject for the measurement of ESR using Westerngreen method. Full blood count parameters were determined using the auto haematology analyzer (Genesis, HA6000, China). Serum ferritin was determined using ELISA method (Melsin Medical, China). All data management and statistical analysis were performed using SPSS software version 26.0 (SPSS Inc., Chicago, USA).

Results: Results showed that there was a statistically significant decrease in neutrophil count, haemoglobin and packed cell volume (p ˂ 0.05) among the anaemic compared to non-anaemic subjects. There were no statistically significant (p>0.05) differences in RBC count, white cell, platelets, MCV, MCH, MCHC, lymphocyte, neutrophil, MXD, RDW, ESR, and ferritin level between the anaemic and non-anaemic subjects. The prevalence of anaemia, iron deficiency anaemia, thrombocytopenia, leukocytosis, leucopenia, lymphopenia, raised RDW, MPV and PLCR among the female subjects were 40.28, 2.7, 23.6, 1.38, 2.77, 1.38, 4.16, 5.55 and 26.38%, respectively. Statistically significant (p< 0.05) negative correlations were observed between selected hematological parameters (PLC vs WBCs; MCV vs RBC; MCHC vs RBCs; MCHC vs PLC; Neutrophils vs MCV and RDW vs MCV) among the subjects. In contrast, we observed statistically significant (p<0.05) positive correlations between Lymphocytes and Neutrophils, MXD and Lymphocytes, and MXD and neutrophils among the subjects. The findings of this study indicates that anaemia, iron deficiency anaemia, and other haematological abnormalities are prevalent among female students of the Usmanu Danfodiyo University, Sokoto, Nigeria.

Conclusion and Recommendations: There is need for routine monitoring of full blood counts, serum ferritin and ESR particularly anaemic female students. Serious attention should be paid by the Nigerian government regarding anaemia among female university students as their academic performance and productivity may be adversely affected by this health condition. Implementation of intervention strategies such as iron fortification, provision of long-lasting insecticide-treated nets (LLINs), intermittent preventive treatment (IPT) of malaria, and regular administration of anthelmintic drugs may be effective in decreasing the prevalence of anaemia among female students in Usmanu Danfodiyo University , Sokoto in particular and Nigeria in general.

Keywords: Anaemia; Female; Undergraduate; Students; Usmanu Danfodiyo University; Sokoto; Nigeria

References

  1. Bruno DB., et al. Worldwide prevalence of anaemia (2008): 1993-2005.
  2. Zahira B. “Socio-cultural factors affecting anaemia and its effect on mother, child health in rural areas of district Faisalabad, Punja, Pakistan”. Pakistan Journal of Nutrition 11 (2010): 545-549.
  3. World Health Organization. “Worldwide prevalence of anaemia 1993-2005. WHO global database on anaemia”. Geneva Switzerland 71 (2005): 16-24.
  4. Malik G., et al. “Haematological Disorders in Pregnancy”. Best Practice and Research Clinical Obstetrics and Gynaecology 26 (2012): 3-24.
  5. World Health Organisation. WHO Vitamin and Mineral Nutrition/ Anaemia (2011).
  6. WHO/UNICEF/UNU. “Iron deficiency anaemia: assessment, prevention, and control”. Geneva: World Health Organization (2001).
  7. World Bank. Public health at a glance (2004).
  8. Nynke VD. “Anaemia and Micronutrient Deficiencies”. British Medical Bulletin 67 (2003): 149-155.
  9. Chaparro CM., et al. “Anemia epidemiology, pathophysiology, and etiology in low- and middle-income countries”. Annals of the New York Academy of Sciences 1450 (2019): 15-31.
  10. Tower J. “Modern Obstetric for Midwives. 2nd edition”. Lloyd Duke Limited, London, (2006): 219-225.
  11. Rohner F., et al. “In a randomized controlled trial of iron fortification, anthelmintic treatment, and preventive treatment of malaria for anemia control in Ivorian children, only treatment shows modest benefit”. The Journal of Nutrition; 140 (2010): 635-641.
  12. Tolentino K., et al. “An update on anemia in less developed countries”. The American Journal of Tropical Medicine and Hygiene 77 (2007): 44-51.
  13. TerKuile FO., et al. “Impact of permethrin treated bed nets on malaria, anemia, and growth in infants in an area of intense perennial malaria transmission in western Kenya”. American Journal Tropical Medicine and Hygiene 68 (2003): 68-77.
  14. Basu S., et al. “Prevalence of anaemia among school going adolescence of Chandigarh”. Indian Pediatric 42 (2007): 593-599.
  15. World Health Organization. “Iron deficiency anaemia. Assessment, Prevention and Control; A guide for programme managers”. UNICEF, United Nations, WHO (2001).
  16. Janz TG., et al. “Emergency medicine practice: Anaemia in the emergency department, evaluation and treatment”. Emergency Medical Practice 15 (2013): 1-15.
  17. National Population Commission (NPC). “National Census Figures”. Abuja, Nigeria (2007).
  18. Taofeek I. “Sample Size Determination”. In: Research Methodology and Dissertation Writing for Health and Allied Health Professionals 1st edition, Cress Global Limited, Abuja (2010): 74-75.
  19. Sheshadri S., et al. “Impact of Iron supplementation of cognitive functions in Pre-school and school age children. The Indian experience”. American Journal of Clinical Nutrition 50 (1989): 675-686.
  20. Shanti D., et al. “Prevalence of anemia among adolescent girls: a school-based study”. International Journal of Basic Applied Medical Research 5 (2015): 95-98.
  21. Rajaratnam J., et al. “Prevalence of anemia among adolescent girls of rural Tamil Nadu”. Indian Pediat 27 (2000): 532-536.
  22. WHO Report, World Prevalence of Anemia. WHO Global Database on Anemia, World Health Organization”. Geneva Switzerland (2008).
  23. Subramaniyan K., et al. “Prevalence of anemia among health science students of a university in South India”. International Journal of Research in Medical Science 4 (2016) :4598-601.
  24. Shill KB., et al. “Prevalence of iron-deficiency anemia among university students in Noakhali region, Bangladesh”. Journal of Health Population and Nutrition 32 (2014): 103-110.
  25. Dey S., et al. “Prevalence of anaemia in women of reproductive age in Meghalaya: a logistic regression analysis”. Turkish Journal of Medical Sciences 40 (2010): 783-789.
  26. Abalkhail B., et al. “Prevalence of daily breakfast intake, iron deficiency anaemia and awareness of being anaemic among Saudi school students”. International Journal of Food Science and Nutrition 53 (2002): 519-528.
  27. Global nutrition targets 2025. Anemia policy brief. (WHO/NMH/NHD/14.4). Geneva; World Health Organization (2014).
  28. Jawed S., et al. “Frequency of nutritional anemia among female medical students of Faisalabad”. Pakistan Journal of Medical Sciences 33 (2017): 398-403.
  29. Ochei JO., et al. “Medical Laboratory Science; Theory and Practice”. TataMcGraw-Hill Publishing Company Limited; New Delhi11008, India (2003):384.
  30. World Health Organization (WHO). “Worldwide prevalence of anaemia 1993-2005. WHO global database on anaemia”. Geneva Switzerland 71 (2005): 16-24.
  31. Onimawo IA., et al. “Assessment of anaemia and iron status of school aged children (aged 7-12years) in rural communities of Abia State, Nigeria”. African Journal of Agriculture, Nutrition and Development 10 (2010): 2570-2586.
  32. Chukwuja JO., et al. “The prevalence of anaemia in rural primary school in Ekwusigo local government area of Anambra State Njgeria”. Oriental Journal of Medicine 126 (2014): 3-4.
  33. Ekwochi E., et al. “Prevalence of iron deficiency anaemia in anaemic under-5 children in Enugu South East Nigeria”. Nigerian Journal of Pediatrics 41 (2014): 2-7.
  34. Anumudu C., et al. “Nutritional anaemia and malaria in pre-school and school age children”. Annual African Medical Journal 7 (2009): 11-17.
  35. Umar RA., et al. “Low prevalence of anaemia in a cohort of pre-school children with acute uncomplicated Falciparum malaria in Nigeria”. Trends in Medical Research 2 (2007): 95-101.
  36. Mannir S. “Anaemia as seen in Hassan Usman Hospital, Katsina”. Biological Environment Science Journal Tropical 3 (2006): 73-75.
  37. Umar RA., et al. “The relationship between the levels of parasitaemia and anaemia in children with malaria”. Sahel Medical Journal 5 (2002): 58-62.
  38. Jiya NM., et al. “Severe malaria anaemia in children. A 22 - month retrospective review” (2014).
  39. DeBenoist B. et al. “Worldwide prevalence of anaemia 1993-2005”. WHO Global Database on Anaemia (2005): 1-51.
  40. Hassan A., et al. “Anemia and Iron Deficiency in Pregnant Women in Zaria, Nigeria”. Sub-Saharan African Journal of Medicine 1 (2014): 36-39.
  41. Anorlu RI., et al. “Socio-demographic factors in anaemia in pregnancy at booking in Lagos Nigeria”. Journal of Obstetrics and Gyneacology 773 (2006):776.
  42. Muoneke VU., et al. “Prevalence and Aetiology of severe anaemia in under -5 Children in Abakiliki south Eastern Nigeria”. Peadiatrics Therapeutic 1 (2011):107.
  43. Erhabor O., et al. “Iron deficiency anaemia among antenatal women in Sokoto, Nigeria”. British Journal of Medical and Health Sciences 1 (2013): 47-57.
  44. Imran TJ., et al. “Pack cell volume of pregnant women attending Dawakin Kudu general hospital, Kano State, Nigeria”. International Journal of Paediatrics and Applied Science 2 (2008): 46-50.
  45. UNICEF/UNU/WHO. Iron deficiency anaemia assessment, prevention and control. 3, 7-8 17-8 17-90 Geneva 71 (2004):16-24.
  46. Shah AY., et al. “Nutritional status of refugee children entering DeKalb County, Georgia”. Journal of Immigrant and Minority Health 16 (2014): 959‑9
  47. Vos T., et al. “Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010”. Lancet 380 (2012): 2163-2196.
  48. Saberi HR., et al. “Relationship of anemia and serum ferritin in medical students”. International Archives Health Sciences (2016): 43-48.
  49. Wirth JP., et al. “Predictors of anemia in women of reproductive age: Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) project”. The American Journal of Clinical Nutrition 106 (2017): 416S-427S.
  50. Siegel EH., et al. “Epidemiology of anemia among 4- to 17 -month-old children living in south central Nepal”. European Journal of Clinical Nutrition 60 (2006): 228-235.
  51. Balci YI., et al. “Prevalence and risk factors of anemia among adolescents in Denizli, Turkey”. Iranian Journal of Pediatrics 22 (2012): 77-81.
  52. Stoltzfus RJ., et al. “Guidelines for the use of iron supplements to prevent and treat iron deficiency anemia”. Washington. DC: ILSI Press (1998):2039.
  53. Bano R., et al. “Nutritional anaemia in the medical students”. Indian Medical Gazette 1 (2012): 16-18.
  54. Shams S., et al. “The prevalence of iron deficiency anaemia in female medical students in Tehran”. Singapore Medical Journal 51 (2010):116-119.
  55. Drew P. “ABC of clinical haematology, Second Edition”. British Medical Journal Books (2003): 1-9.
  56. Asrie F., et al. “Prevalence of thrombocytopenia among pregnant women attending antenatal care service at Gondar University Teaching Hospital in 2014, northwest Ethiopia”. Journal of Blood Medicine 8 (2017): 61-66.
Citation: Erhabor Osaro., et al. “Anaemia among Female Undergraduate Students of Usmanu Danfodiyo University Sokoto, Nigeria”. EC Paediatrics 9.6 (2020): 47-59.

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