Research Article
Volume 9 Issue 6 - 2020
Epidemiological Aspect of Febrile Convulsive Seizures in Infants and Children in Libreville, Gabon
Minko JI1,2, Lembet Mikolo AM1,2, Essola L1,4, Louembet FC1,2, Minto’o S1,2*, Nganga Singatady Zang LM5 and Ategbo SJ2,3
1Centre Hospitalier Universitaire de Libreville-BP, Libreville, Gabon
2Département de Pédiatrie. Faculté de Médecine et des Sciences de la Santé-BP, Owendo, Gabon
3Centre Hospitalier Universitaire Mère-Enfant- Fondation Jeanne Ebori-Libreville, Gabon
4Service des Urgences Pédiatriques du Centre Hospitalier Universitaire de Libreville, Libreville, Gabon
5Ministère de la Santé, Libreville, Gabon
*Corresponding Author: Minto’o S, Centre Hospitalier Universitaire de Libreville-BP, Libreville, Gabon.
Received: March 30, 2020; Published: May 15, 2020




Abstract

A prospective, observational and transverse study, carried out in pediatric emergency units and in-patients at Centre Hospitalier de Libreville and Hôpital Régional de l’Estuaire de Mélen, from May to September 2011, included 99 infants and children aged between 6 months and 15 years admitted for convulsive seizures in a febrile context. These seizures represented 3.0% of paediatric hospitalisations in Libreville.

The mean age was 42.5 ± 31.2 months, with extremes of 6 and 132 months. Sex ratio was 1.2. Most children were under 5 years old. Their parents were mostly High school educated, and without income-generating activities. Birth took place in healthcare centres (97.0%) through vaginal route (97.0%). Histories of convulsions with fever were reported in 25.2% of patients. Simple seizure was the most frequent (64.2%) with a predominance of generalized tonic-clonic seizures. A state of convulsive failure was noted in 10.5% of patients. Malaria was the main cause in 50.5% of patients, including 5 cases of severe malaria, followed by febrile convulsions in 36.4% and purulent meningitis in 17.1% cases. Hypocalcaemia was found in 26.1% of patients. The average hospital stay was 5±2 days. The disease evolution was favourable for 91.9% of children and death was recorded for 4.1%.

Febrile convulsive seizures are a leading cause of hospital admissions in Libreville and the prognosis depends on etiology. In order to improve management of such patients and to avoid sequalae, further bacteriological and virological investigations are needed, as well as ruling out severe malaria or meningitis, reinforcing anti-malaria prevention methods and raising families' awareness about meningitis vaccine.

Keywords: Seizure; Convulsion; Febrile; Child; Prognostic

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Citation: Minko JI., et al. “Epidemiological Aspect of Febrile Convulsive Seizures in Infants and Children in Libreville, Gabon”. EC Paediatrics 9.6 (2020): 33-39.

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