Review Article
Volume 9 Issue 4 - 2020
Down Syndrome Compendium: Article Review
Samia O Massaad*
Department of Anatomy, Faculty of Medicine and Health Sciences, Gadarif University, Gadarif State, Sudan
*Corresponding Author: Samia Othman Massaad, Department of Anatomy, Faculty of Medicine and Health Sciences, Gadarif University, Gadarif State, Sudan.
Received: February 21, 2020; Published: March 14, 2020




Abstract

Down syndrome is the most common genetic syndrome caused by trisomy 21. Individuals with DS are at an increased risk of heart defects, gastro esophageal reflux, celiac disease, hypothyroidism, hearing and vision problems, leukemia, and Alzheimer disease (AD), as well as intellectual disability of varying degrees. The objective of this review is to provide a framework for understanding different aspects of Down syndrome such as brief historical background, Genetics contributions, risk factors, various types, Common features of abnormal phenotype, developmental deficiencies associated with several health problems due to the some genes overexpression.

Keywords: Down Syndrome; Trisomy 21; Chromosome Anomaly

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Citation: Samia Othman Massaad. “Down Syndrome Compendium: Article Review”. EC Paediatrics 9.4 (2020): 54-59.

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