Case Report
Volume 9 Issue 4 - 2020
Twin Pregnancy with Gastroschisis Associated with Sacrococcygeal Teratoma and Limb Abnormalities in both Twins
Nader Al-labede1, Hassan Shora2*, Fatma Attia1, Mona Dandash1, Ahmed Soliman1, Ahmed A Abo-Zaid1 and Mohammed Kamal3
1Fetal Medicine Unit, Department of Obstetrics and Gynecology, Ismailia General Hospital, Egypt
2Department Molecular Biology/Biochemistry, Port-Said University, Egypt
3Department of Obstetrics and Gynecology, Ain Shams University, Egypt
*Corresponding Author: Hassan A Shora, Senior Research Scientist, Head of Medicine and Diabetes Center Port-Said University and Ismailia General Hospital, Egypt.
Received: February 25, 2020; Published: March 12, 2020




Abstract

Objective: Gastroschisis is a congenital malformation characterized by an abdominal wall defect located laterally to a normal umbilicus. The cause of gastroschisis is unknown, but most probably is considered of exogenous factors. Sacrococcygeal teratoma (SCT) is the most common congenital tumor of the newborn. About 20% of SCTs are malignant. We describe the case of a woman with a twin pregnancy in which both twins had gastroschisis associated with sacrococcygeal teratoma in both twins. A thorough search of literature in PubMed for similar cases did not reveal any reported case of gastroschisis Associated with sacrococcygeal teratoma in both twins.

Case Report: A 21 year old, gravida 2. para 0, abortus 1, woman was referred to fetal medicine unit, Ismailia General Hospital at 22 weeks gestation because of diagnosis of a twin pregnancy with gastroschisis in both twins. Unfortunately, gastroschisis was noted in bath twins and another anomalies were observed that were associated with sacrococcygeal teratoma in both twins about 27wks of gestation get spontaneously of preterm labour pain and delivered twins with gastroschisis associated with Sacrococcygeal teratoma. and died within minutes. Both twins presented with a 3-cm abdominal wall defect located to the right side of the umbilicus and a large portion of the bowel protruding that was not covered by a membrane. Histopathology of the placenta revealed that the twins were diamniotic monochorionic. Chromosomal analysis of cord blood showed normal karyotype (46,XX) in both newborns.

Conclusion: Prenatal diagnosis of GS associated with other anomalies should be identified by careful ultrasonographic assessment. Although GS is not usually associated with other anomalies, the present case report makes us aware of the rare incidence of GS with multiple Congenital anomalies and which should be recognized during the prenatal and neonatal periods.

Keywords: Twins Gastroschisis; Sacrococcygeal teratoma

References

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Citation: Nader Al-labede, Hassan Shora, Fatma Attia., et al. “Twin Pregnancy with Gastroschisis Associated with Sacrococcygeal Teratoma and Limb Abnormalities in both Twins”. EC Paediatrics 9.4 (2020): 34-38.

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