Research Article
Volume 13 Issue 4 - 2021
Differential Diagnostics of Hematogenous Osteomyelitis and Malignant Neoplasm of Bone
Ehsan Ul Haq*, Maryam Jamil, Ameer Shabab, Touseef Ali Memon, Nawaf Dehrab, Noor Afsheen and Nur Umar
Orthopaedics and Trauma, Services Hospital Lahore/ Services Institute of Medical Sciences Lahore Pakistan, Pakistan
*Corresponding Author: Ehsan Ul Haq, Orthopaedics and Trauma, Services Hospital Lahore/ Services Institute of Medical Sciences Lahore Pakistan, Pakistan.
Received: November 18, 2021; Published: January 19, 2022


Objectives: To identify the criteria for differential diagnosis in hematogenous osteomyelitis and malignant neoplasms of the bone, evaluate them in quantitative terms and develop a mathematical model.

Methods: A retrospective analysis of data on 127 patients who underwent differential diagnosis between hematogenous osteomyelitis and malignant bone tumors was performed. The accuracy of the initial diagnosis at the outpatient stage was 59.8% (76 observations). Information on 96 patients who were subsequently diagnosed with hematogenous osteomyelitis was compared with data on 31 patients with morphologically confirmed malignant neoplasms of bone. The method of sequential analysis was used.

Results: When studying about retrospective group, a database was created that became the basis for the development of a mathematical model for the differential diagnosis of hematogenous osteomyelitis and malignant bone disease. 14 prognostic criteria were identified, each of which is defined in quantitative terms. These criteria included the age of the patient, gender, concomitant pathology, localization of the pathological process, indicators of laboratory studies, etc. An algorithm for the differential diagnosis of hematogenous osteomyelitis and malignant neoplasms of the bone was developed.

Conclusion: During a prospective study (63 cases), differential diagnosis model was tested. As a result of this, the accuracy of the initial diagnosis at the outpatient stage was 88.9% (56 patients), which made it possible to shorten the examination time and refer patients to specialized hospitals.


Keywords: Hematogenous Osteomyelitis; Malignant Bone Lesion; Differential Diagnosis


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Citation: Ehsan Ul Haq., et al. “Differential Diagnostics of Hematogenous Osteomyelitis and Malignant Neoplasm of Bone”. EC Orthopaedics 13.4 (2022): 07-15.

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