Case Report
Volume 12 Issue 12 - 2021
HIV-Related Rheumatic and Musculoskeletal Disorder Co-Morbidities: Asymptomatic Symmetric Polyarthritis

Chikanza IC1*, Ntshalintshali SD2and Trollip S3

1Department of Rheumatology, The Royal London Hospital, London, United Kingdom
2Division of Rheumatology, Tygerberg Hospital, Stellenbosch University, Cape Town, South Africa
3Department of Medicine, Apex Medical School, Lusaka, Zambia
*Corresponding Author: Chikanza IC, Department of Rheumatology, The Royal London Hospital, London, United Kingdom.
Received: September 30, 2021; Published: November 30, 2021


A number of rheumatic and musculoskeletal disorders (RMD) have now been described in association with HIV infection [1]. HIV-infected individuals are now being diagnosed early and aggressively treated with anti-retroviral therapy (ART) to completely inhibit viral load and replication. As a result, mortality has been reduced to near normal life expectancy. A variety of autoantibodies have also been described. The RMD manifestations reported to date include HIV associated inflammatory arthritis {rheumatoid arthritis (RA), psoriatic arthritis (PsA), undifferentiated spondyloarthropathy, reactive arthritis, autoimmune inflammatory connective tissue disease {CTD} (SLE, Sjogren’s syndrome, sarcoidosis and Behçet’s disease), Diffuse infiltrative lymphocytosis syndrome (DILS) {Anti-Ro/La negative} and polymyositis. Interestingly, polymyositis may even resolve without specific ARV therapy [3]. Some patients may also develop septic arthritis, vasculitis and osteonecrosis.

Keywords: Rheumatic and Musculoskeletal Disorders; Anti-Retroviral Therapy; HIV


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Citation: Chikanza IC., et al. “HIV-Related Rheumatic and Musculoskeletal Disorder Co-Morbidities: Asymptomatic Symmetric Polyarthritis”. EC Orthopaedics 12.12 (2021): 118-123.

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