Research Article
Volume 12 Issue 11 - 2021
Efficiency of Ossein-Hydroxyapatite Complex in the Treatment of Patients with Non-Unions Complicated by Posttraumatic Osteoporosis
SM Kutepov1, SV Gyulnazarova1* and OA Kuznetzova2
1Ural State Medical University of the Health Ministry of the Russian Federation, Ekaterinburg, Russia
2Ural Institute of Traumatology and Orthopaedics Named After V.D. Chaklin, Ekaterinburg, Russia
*Corresponding Author: SV Gyulnazarova, Ural State Medical University of the Health Ministry of the Russian Federation, Ekaterinburg, Russia.
Received: September 13, 2021; Published: October 28, 2021


Comparative analysis of the results of application of ossein-hydroxyapatite complex (OHC) and calcium with vitamin D3 together with surgical treatment of patients with hypoplastic non-unions of femur and shin, complicated by osteoporosis was performed. Patients were operated by open trans osseous osteosynthesis with Ilizarov apparatus without the autobone plasty. After surgery one group of patients had received OHC for 6 months as it was recommended by authors (Patent RF № 2423983). Second group of patients had received calcium with vitamin D3 during the same period of time. Third group did not receive any medicaments. Non-unions of all patients were eliminated without repeated surgery. Analysis of union-time showed the use of OHC or calcium with vitamin D3 promoted significant reduction of the non-union consolidation time. OHC influenced also on bone mineral density of damaged leg positively. It contributed optimization to process of the bone remodeling and provided regression of osteoporosis even in time of the main pathology treatment and later, in 1.5 years of subsequent observation. Results of this investigations has shown high efficiency of OHC in treatment of non-unions complicated by posttraumatic (immobilized) osteoporosis. The use of OHC in treatment of this very difficult orthopaedical pathology is reasonable and efficient.

Keywords:Non-Union; Femur; Shin; Osteoporosis; Ilizarov Apparatus; Ossein-Hydroxyapatite Complex; Bone Mineral Density; Standard Deviationn


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Citation: SV Gyulnazarova., et al. “Efficiency of Ossein-Hydroxyapatite Complex in the Treatment of Patients with Non-Unions Complicated by Posttraumatic Osteoporosis”. EC Orthopaedics 12.11 (2021): 29-35.

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