Research Article
Volume 12 Issue 11 - 2021
Optimization of Treatment of Patients with Tuberculous Spondylitis
GG Golka*, VV Vesnin, VV Burlaka, AO Oliynyk and OG Fadeev
Kharkiv National Medical University, Kharkiv, Ukraine
*Corresponding Author: GG Golka, Kharkiv National Medical University, Kharkiv, Ukraine.
Received: March 26, 2021; Published: October 27, 2021


Introduction: Tuberculous spondylitis (TC) in the structure of osteoarticular tuberculosis in adults occupies a leading position and reaches 40 - 61.5% [2,4,8].

Aim of the Study: Improving the effectiveness of treatment of patients with tuberculous spondylitis.

Materials and Methods of Research: The clinical material of this study were the protocols of clinical and radiological examination, treatment analysis of 60 patients with active tuberculous spondylitis, operated on the clinical bases of the department.

The main group (group №1) included patients (n = 30) with tuberculous spondylitis of the thoracic and lumbar vertebrae, operated using a sliding titanium cage for ventral interbody fusion. A feature of preoperative preparation of patients in this group was the mandatory bacteriological examination before treatment to determine the sensitivity of the Office to ABP, the appointment of a short intensive course of specific antibacterial therapy based on the results of the study for 2 - 3 weeks followed by surgery. The basis for such a short period of preoperative preparation were the results of our experimental study [1]. A feature of the operative stage of treatment in this group of patients was the performance after the sanitizing stage (decompression necrectomy) of anterior spondylodesis using a telescopic titanium cage.

The comparison group (group № 2) included patients (n = 30) with tuberculous spondylitis of the thoracic and lumbar vertebrae using traditional approaches to surgical treatment of TC - preoperative preparation using 3-5 specific ABP without determining the sensitivity for 2 - 3 months with subsequent surgical intervention - decompressive necrectomy of the affected vertebrae and anterior spondylodesis autograft taken from a fragment of the rib (in the case of thoracic access) or from the wing of the iliac bone during surgery on the lumbar spine.

By age, sex, number of affected vertebral motor segments, activity of infectious inflammatory process, patients of the main group and the comparison group are almost identical, so comparing the results of treatment of patients of both groups in the near (3 months) and distant periods (1 - 2 years) is quite correct.

Results of Research and Discussion: For clinical evaluation of the results of treatment of patients of both groups used a score scale proposed by Ulrich EV, Mushkin O. Yu [7].

At the same time excellent results were obtained in 14 patients of the main group (54%) and in 8 - control group (32%); good - in 71 (24.7%) patients of the main group and in 7 (28%) patients of the control group; satisfactory - in 4 (15.4%) patients of the main group and in 7 (28%) of the control group, unsatisfactory - in 3 (12%) patients of the control group, unsatisfactory results in patients of the main group.

The analysis of long-term results testifies to essentially better results of treatment of patients of the main group.


  1. Our proposed method of surgical treatment of vehicles using modern advances in vertebrology (the use of telescopic titanium cages during surgery) after short-term intensive antibacterial therapy, taking into account the previous etiological diagnosis is a promising area for improving surgical treatment.
  2. A comparative study of the effectiveness of treatment of patients of the main and control groups with TC showed that the use of the proposed technique in patients of the main group significantly improved treatment results by significantly reducing the stage of preparation for radical surgery, reducing complications, reducing inpatient treatment and improving quality life.

Keywords: Experimental Vehicle; Ethiological Diagnostics of Vehicle; Optimization of Vehicle Testing; Operative Testing of Vehicle; Results of Testing


  1. Golka GG., et al. “Experimental model of tuberculous spondylitis”. Injury 3-4 (2018): 68-75.
  2. Perelman MI and Levasheva Yu. “Diagnosis and treatment of extrapulmonary tuberculosis”. Practical Guide/Edition. N. Moscow: Medicine and life (2002).
  3. Korzh, A. A., et al. “Surgical access to the thoracic and lumbar vertebrae”. Moscow: Medicine (1968).
  4. Kornev PG. “Osteoarticular tuberculosis surgery: in 3 volumes. Leningrad: Medicine (1971).
  5. Levasheva YuN and Garbuza AE. “Osteoarticular tuberculosis”. Under. edition. Moscow: Medicine and life (2003).
  6. Perelman MI. “Phthisiology: national guidelines”. Moscow: GEOTAR-Media (2007).
  7. Ulrich EV and Mushkin AYu. “Vertebrology in terms, numbers, pictures”. St. Petersburg: ELBI-SPb (2004).
  8. Colmenero JD., et al. “Establishing the diagnosis of tuberculous vertebral osteomyelitis”. European Spine Journal4 (2013): 579-586.
  9. Garg RK and Somvanshi DS. “Spinal tuberculosis: a review”. The Journal of Spinal Cord Medicine5 (2011): 440-454.
Citation: GG Golka., et al. “Optimization of Treatment of Patients with Tuberculous Spondylitis”. EC Orthopaedics 12.10 (2021): 04-13.

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