Case Report
Volume 12 Issue 6 - 2021
Acute Pseudogout Attack Precipitated by Intra-Articular Injection of a Cross-Linked Hyaluronate Combined with Triamcinolone Hexacetonide
Yoon Kam Hon*
Consultant Physician and Rheumatologist, El Shaddai Arthritis and Rheumatism Specialist Medical Centre, Singapore
*Corresponding Author: Yoon Kam Hon, Consultant Physician and Rheumatologist, El Shaddai Arthritis and Rheumatism Specialist Medical Centre, Singapore.
Received: April 30, 2021; Published: May 29, 2021


Intra-articular hyaluronic acid (IAHA) injection is widely used in the day-to-day management of symptomatic osteoarthritis (OA) of the knees with good efficacy and minimal side effects. Occasionally OA and chondrocalcinosis can co-exist in some patients. IAHA injection is widely used in the day-to-day management of symptomatic OA knees with good efficacy and minimal side effects in my clinic. Induction of an acute attack of calcium pyrophosphate dihydrate (CPPD) arthritis by IAHA has been rarely reported. We report a patient who developed acute pseudogout after IA Cingal injection, despite the triamcinolone hexacetonide given in the IA, and also reviewed previous reports and discussed preventive and management approaches to avoid such an unpleasant but, thankfully, a rare occurrence.

Keyword: Pseudogout Trigger; Intra-articular Hyaluronic Acid; Injection


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Citation: Yoon Kam Hon. “Acute Pseudogout Attack Precipitated by Intra-Articular Injection of a Cross-Linked Hyaluronate Combined with Triamcinolone Hexacetonide”. EC Orthopaedics 12.6 (2021): 67-71.

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