Research Article
Volume 11 Issue 11 - 2020
Use of PRP for Split Thickness Skin Graft Donor Sites to Reduce Pain and Promote Faster Healing Rates: A Randomized Controlled Trial
RK Jain and Samarth Gupta*
Department of Plastic Surgery, SMS Hospital, Jaipur, India
*Corresponding Author: Samarth Gupta, Department of Plastic Surgery, SMS Hospital, Jaipur, India.
Received: July 24, 2020; Published: October 31, 2020


Introduction: Platelet Rich Plasma has been vastly utilised in the medical field due to its property to heal the wounds and the multitude of growth factors it contains. Traditionally, donor sites are left to heal with a primary dressing which would otherwise be opened as the wound heals. Various methods of donor site management have been described such as collagen dressings, hydrocolloid, alginate, hydrofiber, silicone dressing, or paraffin gauze. However, it is often encountered that there is a delay in the healing process and accompanied by pain at donor site. Furthermore, in a relatively small population of patients who have a tendency to hypertrophic scar formation, this becomes a challenge for the plastic surgeon. It not only leads to unsightly scars but also additional problems of dryness and itching. This study primarily throws light on the usage of Autologous PRP over Split thickness Skin Graft donor sites to augment healing and reduce pain.

Materials and Methods: The 100 patients enrolled in this study between 2018 - 2019 were divided into two groups of 50 each on a randomized basis, one of which was subjected to use of Autologous PRP, which was topically applied at the donor site and the other control group where the wound was traditionally dressed. Pain scales were measured in the immediate postoperative period as well as at the time of first dressing. Dressing was opened on the 14th postoperative day and observed for healing.

Results: Patients with the PRP group showed statistically significant faster healing at the 14th postoperative day, as compared to the control group which required continuing dressing 3 - 4 weeks. We also measured pain scale in the postoperative period and at the time of first dressing, which was significantly less in the PRP group. Its worthy to mention that a few of the patients who has hypertrophic scars previously, did not develop after the application of PRP.

Conclusion: Application of PRP is a safe, cost effective, easy method to achieve faster healing in graft donor site areas, which is more often than not bothersome to the patients undergoing split thickness grafts. It also reduces the postoperative pain at the donor site. We recommend its use more frequently in managing donor site for Split thickness skin grafts.

Keywords: PRP; Donor Site; Pain; Skin Grafts; Wound Healing


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Citation: RK Jain and Samarth Gupta. “Use of PRP for Split Thickness Skin Graft Donor Sites to Reduce Pain and Promote Faster Healing Rates: A Randomized Controlled Trial”. EC Orthopaedics 11.11 (2020): 69-75.

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