Research Article
Volume 13 Issue 9 - 2022
Prevalence of Symptomatic Dry Eye and its Risk Factors in Central Region, Saudi Arabia: A Cross-Sectional Study
Abdulrahman J Alharbi1*, Amal B Alharbi2, Ayshah S Alajmah3, Aisha A Alghamdi3 and Ahmed Al-Muhaileb4
1Optometry Department, Alrass General Hospital, Qassim Health Cluster, Ministry of Health, Saudi Arabia
2College of Medicine, Qassim University, Saudi Arabia
3Optometry Department, Eye Specialist Center, King Abdulaziz Specialist Hospital, Ministry of Health, Saudi Arabia
4Department of Surgery, Unaizah College of Medicine and Medical Sciences, Qassim University, Saudi Arabia
*Corresponding Author: Abdulrahman J Alharbi, Optometry Department, Alrass General Hospital, Qassim Health Cluster, Ministry of Health, Saudi Arabia.
Received: June 12, 2022; Published: August 18, 2022




Abstract

Background: Different regions indicates different prevalence levels of the dry eye syndrome. Some risk factors are common across all the regions in the world while some are specific to certain regions. Estimating the prevalence levels and determining the risk factor helps in estimating the weight of the issue by the health care providers as well as the government policies to address the health issue.

Purpose: This study aims to evaluate the prevalence and identify possible risk factors for DES in the central region of Saudi Arabia.

Methods: Methods was conducted a prospective descriptive cross-sectional study between May and July 2018. This sample consisted of 604 Saudi including 104 control group. The participants were selected by the criteria of staying in Saudi Arabia for more than 3 years while those from the control group had lived in region for less than six months. All participants answered an electronic self-administered questionnaire which asked about the consent at the beginning, some sociodemographic details, symptoms and risk factors related to DES. To assess ocular symptoms, the Ocular Surface Disease Index (OSDI) score was used. Data were presented as frequency, mean, median, and standard deviation. A t-test was used to compare between different age groups. Multivariate regression was used to identify possible predictors of DES.

Results: The prevalence level was 59.1% which is statistically high. Most affected were the old and the university students. Female students were affected than male students. The risk factors are hot climatic conditions experienced with the region, old age, refractive surgery and use of contact lenses.

Conclusion: Symptomatic DES is highly prevalent among central region population. Main predictors of DES were age, hot weather, use of contact lens and refractive surgery. The recommendation is that the concern of increasing rate of use of contact lenses among students without following health guidelines should be addressed.

Keywords: Dry Eye Disease; Dry Eye Syndrome (DES); OSDI; Dry Eye; Central Region; KSA

References

  1. Brewitt H and Sistani F. “Dry eye disease: the scale of the problem”. Survey of Ophthalmology2 (2001): S199-202.
  2. The definition and classification of dry eye disease: report of the Definition and Classification Subcommittee of the International Dry Eye Work Shop”. The Ocular Surface2 (2007): 75-92.
  3. Lee AJ., et al. “Prevalence and risk factors associated with dry eye symptoms: a population based study in Indonesia”. British Journal of Ophthalmology12 (2002): 1347-1351.
  4. Tong L., et al. “Impact of symptomatic dry eye on vision-related daily activities: the Singapore Malay Eye Study”. Eye9 (2010): 1486-1491.
  5. Pouyeh B., et al. “Impact of ocular surface symptoms on quality of life in a United States veterans affairs population”. American Journal of Ophthalmology6 (2012): 1061-1066.
  6. Alshamrani AA., et al. “Prevalence and Risk Factors of Dry Eye Symptoms in a Saudi Arabian Population”. Middle East African Journal of Ophthalmology2 (2017): 67-73.
  7. Bandeen-Roche K., et al. “Self-reported assessment of dry eye in a population-based setting”. Investigative Ophthalmology and Visual Science12 (1997): 2469-2475.
  8. Begley CG., et al. “Characterization of ocular surface symptoms from optometric practices in North America”. Cornea6 (2001): 610-618.
  9. Lemp M. “Epidemiology and classification of dry eyes”. In: Sullivan DA, et al, ed Lacrimal gland, tear film and dry eye syndromes 2. New York: Plenum Press (1998): 791-803.
  10. Clegg JP., et al. “The annual cost of dry eye syndrome in France, Germany, Italy, Spain, Sweden and the United Kingdom among patients managed by ophthalmologists”. Ophthalmic Epidemiology4 (2006): 263-274.
  11. Albietz JM. “Prevalence of dry eye subtypes in clinical optometry practice”. Optometry and Vision Science7 (2000): 357-363.
  12. Schiffman RM., et al. “Reliability and validity of the Ocular Surface Disease Index”. Archives of Ophthalmology5 (2000): 615-621.
  13. Moss SE., et al. “Prevalence of and risk factors for dry eye syndrome”. Archives of Ophthalmology9 (2000): 1264-1268.
  14. Lin P-Y., et al. “Prevalence of dry eye among an elderly Chinese population in Taiwan: the Shihpai Eye Study”. Ophthalmology6 (2003): 1096-1101.
  15. Hashemi H., et al. “Prevalence of dry eye syndrome in an adult population”. Clinical and Experimental Ophthalmology3 (2014): 242-248.
  16. Schein OD., et al. “Prevalence of dry eye among the elderly”. American Journal of Ophthalmology6 (1997): 723-728.
  17. McCarty CA., et al. “The epidemiology of dry eye in Melbourne, Australia”. Ophthalmology6 (1998): 1114-1119.
  18. Rege A., et al. “A Clinical Study of Subtype-based Prevalence of Dry Eye”. Journal of Clinical and Diagnostic Research10 (2013): 2207-2210.
  19. Schaumberg DA., et al. “Hormone replacement therapy and dry eye syndrome”. The Journal of the American Medical Association17 (2001): 2114-2119.
  20. Shimmura S., et al. “Results of a population-based questionnaire on the symptoms and lifestyles associated with dry eye”. Cornea4 (1999): 408-411.
  21. Bukhari A., et al. “Prevalence of dry eye in the normal population in Jeddah, Saudi Arabia”. Orbit6 (2009): 392-397.
  22. Jie Y., et al. “Prevalence of dry eye among adult Chinese in the Beijing Eye Study”. Eye3 (2009): 688-693.
  23. Tan LL., et al. “Prevalence of and risk factors for symptomatic dry eye disease in Singapore”. Clinical and Experimental Optometry1 (2015): 45-53.
  24. Wolkoff P., et al. “The modern office environment desiccates the eyes?” Indoor Air Quality4 (2006): 258-265.
  25. Wolkoff P., et al. “Eye complaints in the office environment: precorneal tear film integrity influenced by eye blinking efficiency”. Occupational and Environmental Medicine1 (2005): 4-12.
  26. Galor A., et al. “Prevalence and risk factors of dry eye syndrome in a United States veterans affairs population”. American Journal of Ophthalmology3 (2011): 377-384.
  27. Alhamyani A., et al. “Prevalence of dry eye symptoms and its risk factors among patients of King Abdulaziz Specialist Hospital (Taif), Saudi Arabia”. Saudi Journal for Health Sciences3 (2017): 140.
  28. Titiyal JS., et al. “Prevalence and risk factors of dry eye disease in North India: Ocular surface disease index-based cross-sectional hospital study”. Indian Journal of Ophthalmology2 (2018): 207-211.
Citation: Abdulrahman J Alharbi., et al. “Prevalence of Symptomatic Dry Eye and its Risk Factors in Central Region, Saudi Arabia: A Cross-Sectional Study”. EC Ophthalmology 13.9 (2022): 01-07.

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