Research Article
Volume 12 Issue 9 - 2021
Effect of Age, Gender, Region, and Refractive Errors on Central Corneal Thickness among Saudi Population; A Cross-Sectional Study
Faisal Alanizy1, Albanderi Alhamzah2,3*, Adel Alluhaidan1, Tariq Aldabasia3, Mazen Alsamnan4, Mohammed Taha1,3, Ahmed Mohamed1, AbdulMalik Abbasi1 and Tariq Almudhaiyan1,2,3
1Department of surgery, division of ophthalmology, National Guard Health affairs, Riyadh, Saudi Arabia
2King Saud bin Abdulaziz Unevirsity for Health Sciences, Riyadh, Saudi Arabia
3King Abdullah International Medical Research Center (KAIMRC), Riyadh, Saudi Arabia
4Department of surgery, division of ophthalmology, Security Forces Hospital, Salah Aldeen Road, Riyadh, Saudi Arabia
*Corresponding Author: Albanderi Alhamzah, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
Received: July 29, 2021; Published: August 30, 2021


Purpose: To determine the average central corneal thickness (CCT) in healthy Saudi adults and to analyze the variations based on gender, age, region, and refractive errors.

Methods: Cross-sectional study of average CCT of subjects between the ages of 20 - 40 who were randomly invited to participate at a gathering center in Riyadh, Saudi Arabia. Volunteers were excluded if they had corneal or ocular pathology, a history of ocular surgery or trauma, and contact lenses wear within 7 days of data collection. CCT was measured using Scheimpflug tomography. Statistical analysis was performed to determine any association of CCT with age, gender, refractive error, and geographic location. A P value less than 0.05 was considered statistically significant.

Results: A total of 379 subjects (755 eyes) with a mean age of 28.88 ± 5.77 years. More than half of the participants were females 244 (64.4%). The mean CCT was 544.32 ± 36.25 μm (range, 447 - 654 μm). CCT was statistically significantly influenced by age (P = 0.0001) where CCT was significantly lower as age increases. Although there was no statistically significant relationship between CCT and regions, nor refractive errors. A tendency toward thinner cornea in participants from north and west regions (P > 0.05) and among hyperopic eyes (P-value 0.06).

Conclusions: The average CCT in the healthy adult Saudi population was comparable to the regional and global averages. There was a significant negative association between age and CCT, where CCT values decrease with older ages. Hyperopic eyes, north and west regions have a tendency to a thinner CCT.

Keywords: Central Corneal Thickness; Pachymetry; Scheimpflug Tomography; Saudi Arabia


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Citation: Tariq Almudhaiyan., et al. “Effect of Age, Gender, Region, and Refractive Errors on Central Corneal Thickness among Saudi Population; A Cross-Sectional Study”. EC Ophthalmology 12.9 (2021): 34-40.

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