Research Artilce
Volume 11 Issue 11 - 2020
Unilateral Inflammation of Proximal Lacrimal Drainage System
Titap Yazicioğlu* and Şaban Şimşek
Department of Ophthalmology, Kartal Dr. Lutfi Kirdar Education and Training Hospital, Istanbul, Turkey
*Corresponding Author: Titap Yazicioğlu, Department of Ophthalmology, Kartal Dr. Lutfi Kirdar Education and Training Hospital, Istanbul, Turkey.
Received: September 16, 2020; Published: October 31, 2020


Objective: To evaluate the efficacy of simple curettage in the treatment of persistent or recurrent canaliculitis patients which often misdiagnosed.

Methods: The medical records of 5 patients with a history of canaliculitis-related symptoms for minimum 8 months and complaining about tenderness, recurrent epiphora with discharge, were reviewed retrospectively. All patients with clinically detectable canalicular concretions were treated expressible drainage and simple curettage (without canaliculotomy). During the 9 months of follow-up period, no further symptoms was observed, and canaliculitis was totally resolved in all of the patients.

Results: Five patients with a mean age of 52.2 ± 8.0 years (range, 45 - 65 years) were included in the study. Of the patients, 2 were women, and 3 were men. The mean duration of symptoms was 8.6 ± 2.2 months (range, 6 - 12) months. Epiphora, recurrent conjunctivitis, swelling around the canaliculus, and mucopurulent punctal discharge were present in all of the patients. Microbiological examination of the sample was reported as Streptomyces epidermidis.

Conclusion: Canaliculitis is an uncommon, and often misdiagnosed inflammation of the lacrimal canalicular system. As it mimics many other common ocular conditions, there is usually a delay in the treatment. The patients with chronic conjunctivitis and lacrimal infection must be examined carefully for canaliculitis and can be easily treated with simple curettage and antibiotics.

Keywords: Chronic Canaliculitis; Canalicular Concretions; Canalicular Curettage


  1. Zhang Q., et al. “Clinical Characteristics, Treatment Patterns, and Outcomes of Primary Canaliculitis among Patients in Beijing, China”. Bio Med Research International (2015): 904756.
  2. Xang S., et al. “Clinical features and surgical outcomes of primary canaliculitis with concretions”. Medicine9 (2017): 1-6.
  3. Kim U., et al. “Primary canaliculitis: The incidence, clinical features, outcome and long-term epiphora after snip–punctoplasty and curettage”. Saudi Journal of Ophthalmology 29 (2025): 274-277.
  4. Ana L Basílio AL., et al. “Chronic lacrimal canaliculitis - the answer to a three-year history of red eye”. Arquivos Brasileiros de Oftalmologia 4 (2018): 341-343.
  5. Yaman A., et al. “Kronik Kanalikülit Olgularinda Kanalikülotomi ile Kanalikül Küretaji”. Turkiye Klinikleri Journal of Ophthalmology 18 (2009): 1-6.
  6. Duru Z., et al. “Sekonder glokom ile başvuran primer kronik kanalikülit olgusu”. Turkiye Klinikleri Journal of Ophthalmology 4 (2024): 243-246.
  7. Jin X., et al. “A treatment method for chornic suppurative lacrimal canaliculitis using chalazion forceps”. Indian Journal of Ophthalmology 8 (2016): 589-592.
  8. Yilmaz MB., et al. “Kanalikülit farkindaliği”. Turkish Journal of Ophthalmology 46 (2016): 25-29.
  9. Singh M., et al. “Primary lacrimal canaliculitis-A clinical entity often misdiagnosed. Case report”. Journal of Current Ophthalmology 20 (2017): 1-4.
  10. Park A., et al. “Pediatric canaliculitis and stone formation”. Ophthalmic Plastic and Reconstructive Surgery 20 (2004): 243-246.
  11. Kaliki S., et al. “Primary canaliculitis: clinical features, microbiological profile, and management outcome”. Ophthalmic Plastic and Reconstructive Surgery 28 (2012): 355-360.
  12. Nair AG., et al. “Actinomycetes canaliculitis complicating congenital nasolacrimal duct obstruction in an infant”. Indian Journal of Ophthalmology 4 (2020): 574-576.
  13. Xu J., et al. “Novel Therapy for Primary Canaliculitis A Pilot Study of Intracanalicular Ophthalmic Corticosteroid/Antibiotic Combination Ointment Infiltration”. Medicine39 (2015): 1-6.
  14. Pavilack MA and Frueh BR. “Through curettage in the treatment of chronic canaliculitis”. Archives of Ophthalmology 110 (1992): 200-202.
  15. Anand S., et al. “Canaliculitis: The incidence of long-term epiphora following canaliculotomy”. Orbit 23 (2004): 19-26.
  16. Vécsei VP., et al. “Canaliculitis: Difficulties in diagnosis, differential diagnosis and comparison between conservative and surgical treatment”. Ophthalmologica 208 (1994): 314-317.
  17. Lee MJ., et al. “One-snip punctoplasty and canalicular curettage through the punctum: a minimally invasive surgical procedure for primary canaliculitis”. Ophthalmology10 (2009): 2027-2030.
  18. Zaveri J and Cohen AJ. “Lacrimal canaliculitis”. Saudi Journal of Ophthalmology 1 (2014): 3-5.
  19. Gogandy M., et al. “Clinical features and bacteriology of lacrimal canaliculitis in patients presenting to a tertiary eye care center in the Middle East”. Saudi Journal of Ophthalmology 1 (2014): 31-35.
Citation: Titap Yazicioğlu and Şaban Şimşek. “Unilateral Inflammation of Proximal Lacrimal Drainage System”. EC Ophthalmology 11.11 (2020): 40-44.

PubMed Indexed Article

EC Pharmacology and Toxicology
LC-UV-MS and MS/MS Characterize Glutathione Reactivity with Different Isomers (2,2' and 2,4' vs. 4,4') of Methylene Diphenyl-Diisocyanate.

PMID: 31143884 [PubMed]

PMCID: PMC6536005

EC Pharmacology and Toxicology
Alzheimer's Pathogenesis, Metal-Mediated Redox Stress, and Potential Nanotheranostics.

PMID: 31565701 [PubMed]

PMCID: PMC6764777

EC Neurology
Differences in Rate of Cognitive Decline and Caregiver Burden between Alzheimer's Disease and Vascular Dementia: a Retrospective Study.

PMID: 27747317 [PubMed]

PMCID: PMC5065347

EC Pharmacology and Toxicology
Will Blockchain Technology Transform Healthcare and Biomedical Sciences?

PMID: 31460519 [PubMed]

PMCID: PMC6711478

EC Pharmacology and Toxicology
Is it a Prime Time for AI-powered Virtual Drug Screening?

PMID: 30215059 [PubMed]

PMCID: PMC6133253

EC Psychology and Psychiatry
Analysis of Evidence for the Combination of Pro-dopamine Regulator (KB220PAM) and Naltrexone to Prevent Opioid Use Disorder Relapse.

PMID: 30417173 [PubMed]

PMCID: PMC6226033

EC Anaesthesia
Arrest Under Anesthesia - What was the Culprit? A Case Report.

PMID: 30264037 [PubMed]

PMCID: PMC6155992

EC Orthopaedics
Distraction Implantation. A New Technique in Total Joint Arthroplasty and Direct Skeletal Attachment.

PMID: 30198026 [PubMed]

PMCID: PMC6124505

EC Pulmonology and Respiratory Medicine
Prevalence and factors associated with self-reported chronic obstructive pulmonary disease among adults aged 40-79: the National Health and Nutrition Examination Survey (NHANES) 2007-2012.

PMID: 30294723 [PubMed]

PMCID: PMC6169793

EC Dental Science
Important Dental Fiber-Reinforced Composite Molding Compound Breakthroughs

PMID: 29285526 [PubMed]

PMCID: PMC5743211

EC Microbiology
Prevalence of Intestinal Parasites Among HIV Infected and HIV Uninfected Patients Treated at the 1o De Maio Health Centre in Maputo, Mozambique

PMID: 29911204 [PubMed]

PMCID: PMC5999047

EC Microbiology
Macrophages and the Viral Dissemination Super Highway

PMID: 26949751 [PubMed]

PMCID: PMC4774560

EC Microbiology
The Microbiome, Antibiotics, and Health of the Pediatric Population.

PMID: 27390782 [PubMed]

PMCID: PMC4933318

EC Microbiology
Reactive Oxygen Species in HIV Infection

PMID: 28580453 [PubMed]

PMCID: PMC5450819

EC Microbiology
A Review of the CD4 T Cell Contribution to Lung Infection, Inflammation and Repair with a Focus on Wheeze and Asthma in the Pediatric Population

PMID: 26280024 [PubMed]

PMCID: PMC4533840

EC Neurology
Identifying Key Symptoms Differentiating Myalgic Encephalomyelitis and Chronic Fatigue Syndrome from Multiple Sclerosis

PMID: 28066845 [PubMed]

PMCID: PMC5214344

EC Pharmacology and Toxicology
Paradigm Shift is the Normal State of Pharmacology

PMID: 28936490 [PubMed]

PMCID: PMC5604476

EC Neurology
Examining those Meeting IOM Criteria Versus IOM Plus Fibromyalgia

PMID: 28713879 [PubMed]

PMCID: PMC5510658

EC Neurology
Unilateral Frontosphenoid Craniosynostosis: Case Report and a Review of the Literature

PMID: 28133641 [PubMed]

PMCID: PMC5267489

EC Ophthalmology
OCT-Angiography for Non-Invasive Monitoring of Neuronal and Vascular Structure in Mouse Retina: Implication for Characterization of Retinal Neurovascular Coupling

PMID: 29333536 [PubMed]

PMCID: PMC5766278

EC Neurology
Longer Duration of Downslope Treadmill Walking Induces Depression of H-Reflexes Measured during Standing and Walking.

PMID: 31032493 [PubMed]

PMCID: PMC6483108

EC Microbiology
Onchocerciasis in Mozambique: An Unknown Condition for Health Professionals.

PMID: 30957099 [PubMed]

PMCID: PMC6448571

EC Nutrition
Food Insecurity among Households with and without Podoconiosis in East and West Gojjam, Ethiopia.

PMID: 30101228 [PubMed]

PMCID: PMC6086333

EC Ophthalmology
REVIEW. +2 to +3 D. Reading Glasses to Prevent Myopia.

PMID: 31080964 [PubMed]

PMCID: PMC6508883

EC Gynaecology
Biomechanical Mapping of the Female Pelvic Floor: Uterine Prolapse Versus Normal Conditions.

PMID: 31093608 [PubMed]

PMCID: PMC6513001

EC Dental Science
Fiber-Reinforced Composites: A Breakthrough in Practical Clinical Applications with Advanced Wear Resistance for Dental Materials.

PMID: 31552397 [PubMed]

PMCID: PMC6758937

EC Microbiology
Neurocysticercosis in Child Bearing Women: An Overlooked Condition in Mozambique and a Potentially Missed Diagnosis in Women Presenting with Eclampsia.

PMID: 31681909 [PubMed]

PMCID: PMC6824723

EC Microbiology
Molecular Detection of Leptospira spp. in Rodents Trapped in the Mozambique Island City, Nampula Province, Mozambique.

PMID: 31681910 [PubMed]

PMCID: PMC6824726

EC Neurology
Endoplasmic Reticulum-Mitochondrial Cross-Talk in Neurodegenerative and Eye Diseases.

PMID: 31528859 [PubMed]

PMCID: PMC6746603

EC Psychology and Psychiatry
Can Chronic Consumption of Caffeine by Increasing D2/D3 Receptors Offer Benefit to Carriers of the DRD2 A1 Allele in Cocaine Abuse?

PMID: 31276119 [PubMed]

PMCID: PMC6604646

EC Anaesthesia
Real Time Locating Systems and sustainability of Perioperative Efficiency of Anesthesiologists.

PMID: 31406965 [PubMed]

PMCID: PMC6690616

EC Pharmacology and Toxicology
A Pilot STEM Curriculum Designed to Teach High School Students Concepts in Biochemical Engineering and Pharmacology.

PMID: 31517314 [PubMed]

PMCID: PMC6741290

EC Pharmacology and Toxicology
Toxic Mechanisms Underlying Motor Activity Changes Induced by a Mixture of Lead, Arsenic and Manganese.

PMID: 31633124 [PubMed]

PMCID: PMC6800226

EC Neurology
Research Volunteers' Attitudes Toward Chronic Fatigue Syndrome and Myalgic Encephalomyelitis.

PMID: 29662969 [PubMed]

PMCID: PMC5898812

EC Pharmacology and Toxicology
Hyperbaric Oxygen Therapy for Alzheimer's Disease.

PMID: 30215058 [PubMed]

PMCID: PMC6133268

News and Events

April Issue Release

We always feel pleasure to share our updates with you all. Here, notifying you that we have successfully released the April issue of respective journals and the latest articles can be viewed on the current issue pages.

Submission Deadline for upcoming Issue

Ecronicon delightfully welcomes all the authors around the globe for effective collaboration with an article submission for the upcoming issue of respective journals. Submissions are accepted on/before April 26, 2021.

Certificate of Publication

Ecronicon honors with a "Publication Certificate" to the corresponding author by including the names of co-authors as a token of appreciation for publishing the work with our respective journals.

Best Article of the Issue

Editors of respective journals will always be very much interested in electing one Best Article after each issue release. The authors of the selected article will be honored with a "Best Article of the Issue" certificate.

Certifying for Review

Ecronicon certifies the Editors for their first review done towards the assigned article of the respective journals.

Latest Articles

The latest articles will be updated immediately on the articles in press page of the respective journals.

Immediate Assistance

The prime motto of this team is to clarify all the queries without any delay or hesitation to avoid the inconvenience. For immediate assistance on your queries please don't hesitate to drop an email to