Abstract
Purpose: To determine the therapeutic effect of Corn silk (Zea mays Linn) on intraocular pressure and blood pressure.
Methods: 75 subjects (29 males and 46 females) within the ages of 16 - 30 years, with mean age of 21 ± 3.19years were used. The baseline readings of intraocular pressure and blood pressure were taken and recorded prior to the administration of corn silk extract (100 mls). The intraocular pressure and blood pressure were measured and recorded 90 minutes, 120 minutes, 150 minutes, 180 minutes and 210minutes post administration of corn silk extract.
Results: The mean baseline intraocular pressure (IOP) was 14.8 ± 2.0 mmHg and decreased to 10.5 ± 1.8 mmHg at 150 minutes post administration and increased towards baseline at 210 minutes to 14.1 ± 1.8 mmHg. The mean baseline blood pressure (SBP/DBP) was 111.3 ± 7.8/71.5 ± 7.7 and decreased to 94.3 ± 11.8/61.8 ± 7.0 at 150 minutes but did not increase towards baseline values at 210 minutes rather remained reduced at 94.3 ± 12.3/62.1 ± 7.3.
Conclusion: Corn silk aqueous extract reduces IOP and BP although its effect on IOP is not sustained thus it can be used as supplement in the management of ocular hypertension and hypertension especially due to the fact that it being a waste material in many kitchens is relatively inexpensive and easy to access.
Keywords: Corn Silk (Zea mays Linn); Intraocular Pressure; Blood Pressure
References
- Faranados N., et al. “Contact lens sensor in ocular diagnosis”. Advanced Health Care Materials 4.6 (2014): 792-810.
- Ira SS. “Aqueous humor dynamics”. American Journal of Optometric Physiology 53.1 (1977): 202-201.
- Kanski JJ. “Clinical ophthalmology. 5th edition. China: Butter worth-Heinemann (2012): 194-217.
- Flammer J. Journal of Glaucoma Bern: Hogrefe and Huber Publishers (2003).
- Gunnar S., et al. “Intraocular pressure fluctuation in professional brass and woodwind”. Graefe’s Archive for Clinical and Experimental Ophthalmology 249.6 (2011): 895-901.
- Sembulingam K and Sembulingam P. “Essentials of medical physiology (6th edition)”. New Delhi: Jay pee Brothers medicals publishers (2010): 923-930.
- Van-Berg LHM., et al. “Relationship between waking and sleeping blood pressure and catecholamine changes in African American and European American women”. Blood Pressure Monitory Journal 13.5 (2008): 257-262.
- Chiolero A. “The quest for blood pressure reference values in children”. Journal of Hypertension 32.3 (2014): 477-478.
- Catriona S., et al. “Sex differences in blood pressure and its relationship to body composition and metabolism in adolescence”. Archive of Pediatric Adolescence Medic 163.9 (2009): 818-825.
- Sullivan J. “Causes of gender differences in blood pressure and kidney damage under study”. Science Daily 5 (2007): 210-225.
- Velazquez DVO., et al. “Zea mays L. extracts modify glomerular functions and potassium urinary excretion in conscious rats”. Journal of Phytochemical Medicine 12.1 (2005): 363-369.
- Abendroth LJ., et al. Corn growth and development USA: Lowa street university extension publication (2011): 105-120.
- Zeringue HJ. “Identification and effects of maize silk volatiles on cultures of aspergillus flavus”. Journal of Agric Food Chemistry 1.1 (2000): 5-12.
- Habtemariam S. “Extract of corn silk inhibits lipopolysaccharide induced cell adhesion”. Journal of Medicinal Plant and Natural Product Research 64.1 (1998): 314-318.
- Owoyele BV., et al. “Phytochemical constituents of aqueous corn silk extracts”. Research Journal of Pharmaceutical, Biological and Chemical Sciences 2.1 (2010): 30-34.
- Liu J., et al. “Supercritical fluid extraction of flavonoids from Maydis stigma and its nitrate-scavenging ability”. Food Bioproduction Process 89.2 (2011): 333-339.
- Pietta PG. “Flavonoids and antioxidants”. Journal of National Production 63.2 (2000): 1035-1042.
- Haloui M., et al. “Experimental diuretic effects of Rosmarinus officinalis and Centaurium erythraea”. Journal of Ethnopharmacology 71.1 (2000): 465-472.
- Tomic D. Framakoterapija. France: Beograd-Zagreb (1984): 420-425.
- Association of Analytical Communities. Official methods of analysis, Maryland USA: AOAC international (1996): 45-55.
- Seebauer JR., et al. “Amino acid metabolism in maize ear short: implications of assimilate preconditioning and Nitrogen signaling”. Journal of Plant Physiology 136.2 (2004): 4326-4334.
- Maksimovic ZA and Kovacevic N. “Preliminary assay on the antioxidative activity of maydis stigma extracts”. Fitoterapia 74.1 (2003): 144-147.
- Pearson G., et al. “Mitogen- activated protein (MAD) kinase pathways regulation and physiological functions”. Journal of Endocrine Review 22.1 (2001): 153-183.
- Guo J., et al. “Effect of corn silk on glycaemic metabolism”. Journal of Nutrition and Metabolism 6.1 (2009): 47-50.
- Min OJ., et al. “Effect of maydis stigma water extract on adipogenesis and blood glucose in mice”. Korean Journal of Pharmacognosy 42.1 (2011): 201-208.
- Jiyang G., et al. “The effect of corn silk on glycaemia metabolism”. Journal of Nutrition Metabolism 6.1 (2009): 47-52.
- Frampton P., et al. “Diurnal variation of intraocular pressure and the overriding effects on sleep”. American Journal of Optometric Physiology 64.1 (2000): 54-61.
- George GO and Idu FK. “Corn silk aqueous extract and intraocular pressure of systemic and non- systemic hypertensive subjects”. Journal of Clinical Experimental Optometry 6.2 (2015): 10-15.
- Tucakor S. “Lecenje bilijemia”. France: Beograd-Zagreb (1990): 310-320.
- Czernichow S., et al. “Antioxidant and supplementation does not affect plasma glucose in the supplementation. With antioxidant vitamins and mineral association with dietary intake and plasma concentrations”. American Journal of Clinical Nutrition 84.2 (2004): 395-409.
- Montezano AC and Touyz RM. “Oxidative stress and hypertension: Experimental evidence and clinical controversies”. Journal of Vision Science 51.1 (2012): 1599-1605.
- Vaajanen A., et al. “Is there a relationship between blood pressure and intraocular pressure?: An experimental study in hypertensive rats”. Current Eye Research 33.1 (2008): 325-332.
- Castejon H., et al. “Effect of acute increase in blood pressure on intraocular pressure in pigs and human”. Invest Ophthalmology Vision Science 51.1 (2010): 1599-1605.
Journal Menu
PubMed Indexed Article
EC Pharmacology and Toxicology
LC-UV-MS and MS/MS Characterize Glutathione Reactivity with Different Isomers (2,2' and 2,4' vs. 4,4') of Methylene Diphenyl-Diisocyanate.
PMID: 31143884 [PubMed]
PMCID: PMC6536005
EC Pharmacology and Toxicology
Alzheimer's Pathogenesis, Metal-Mediated Redox Stress, and Potential Nanotheranostics.
PMID: 31565701 [PubMed]
PMCID: PMC6764777
EC Neurology
Differences in Rate of Cognitive Decline and Caregiver Burden between Alzheimer's Disease and Vascular Dementia: a Retrospective Study.
PMID: 27747317 [PubMed]
PMCID: PMC5065347
EC Pharmacology and Toxicology
Will Blockchain Technology Transform Healthcare and Biomedical Sciences?
PMID: 31460519 [PubMed]
PMCID: PMC6711478
EC Pharmacology and Toxicology
Is it a Prime Time for AI-powered Virtual Drug Screening?
PMID: 30215059 [PubMed]
PMCID: PMC6133253
EC Psychology and Psychiatry
Analysis of Evidence for the Combination of Pro-dopamine Regulator (KB220PAM) and Naltrexone to Prevent Opioid Use Disorder Relapse.
PMID: 30417173 [PubMed]
PMCID: PMC6226033
EC Anaesthesia
Arrest Under Anesthesia - What was the Culprit? A Case Report.
PMID: 30264037 [PubMed]
PMCID: PMC6155992
EC Orthopaedics
Distraction Implantation. A New Technique in Total Joint Arthroplasty and Direct Skeletal Attachment.
PMID: 30198026 [PubMed]
PMCID: PMC6124505
EC Pulmonology and Respiratory Medicine
Prevalence and factors associated with self-reported chronic obstructive pulmonary disease among adults aged 40-79: the National Health and Nutrition Examination Survey (NHANES) 2007-2012.
PMID: 30294723 [PubMed]
PMCID: PMC6169793
EC Dental Science
Important Dental Fiber-Reinforced Composite Molding Compound Breakthroughs
PMID: 29285526 [PubMed]
PMCID: PMC5743211
EC Microbiology
Prevalence of Intestinal Parasites Among HIV Infected and HIV Uninfected Patients Treated at the 1o De Maio Health Centre in Maputo, Mozambique
PMID: 29911204 [PubMed]
PMCID: PMC5999047
EC Microbiology
Macrophages and the Viral Dissemination Super Highway
PMID: 26949751 [PubMed]
PMCID: PMC4774560
EC Microbiology
The Microbiome, Antibiotics, and Health of the Pediatric Population.
PMID: 27390782 [PubMed]
PMCID: PMC4933318
EC Microbiology
Reactive Oxygen Species in HIV Infection
PMID: 28580453 [PubMed]
PMCID: PMC5450819
EC Microbiology
A Review of the CD4 T Cell Contribution to Lung Infection, Inflammation and Repair with a Focus on Wheeze and Asthma in the Pediatric Population
PMID: 26280024 [PubMed]
PMCID: PMC4533840
EC Neurology
Identifying Key Symptoms Differentiating Myalgic Encephalomyelitis and Chronic Fatigue Syndrome from Multiple Sclerosis
PMID: 28066845 [PubMed]
PMCID: PMC5214344
EC Pharmacology and Toxicology
Paradigm Shift is the Normal State of Pharmacology
PMID: 28936490 [PubMed]
PMCID: PMC5604476
EC Neurology
Examining those Meeting IOM Criteria Versus IOM Plus Fibromyalgia
PMID: 28713879 [PubMed]
PMCID: PMC5510658
EC Neurology
Unilateral Frontosphenoid Craniosynostosis: Case Report and a Review of the Literature
PMID: 28133641 [PubMed]
PMCID: PMC5267489
EC Ophthalmology
OCT-Angiography for Non-Invasive Monitoring of Neuronal and Vascular Structure in Mouse Retina: Implication for Characterization of Retinal Neurovascular Coupling
PMID: 29333536 [PubMed]
PMCID: PMC5766278
EC Neurology
Longer Duration of Downslope Treadmill Walking Induces Depression of H-Reflexes Measured during Standing and Walking.
PMID: 31032493 [PubMed]
PMCID: PMC6483108
EC Microbiology
Onchocerciasis in Mozambique: An Unknown Condition for Health Professionals.
PMID: 30957099 [PubMed]
PMCID: PMC6448571
EC Nutrition
Food Insecurity among Households with and without Podoconiosis in East and West Gojjam, Ethiopia.
PMID: 30101228 [PubMed]
PMCID: PMC6086333
EC Ophthalmology
REVIEW. +2 to +3 D. Reading Glasses to Prevent Myopia.
PMID: 31080964 [PubMed]
PMCID: PMC6508883
EC Gynaecology
Biomechanical Mapping of the Female Pelvic Floor: Uterine Prolapse Versus Normal Conditions.
PMID: 31093608 [PubMed]
PMCID: PMC6513001
EC Dental Science
Fiber-Reinforced Composites: A Breakthrough in Practical Clinical Applications with Advanced Wear Resistance for Dental Materials.
PMID: 31552397 [PubMed]
PMCID: PMC6758937
EC Microbiology
Neurocysticercosis in Child Bearing Women: An Overlooked Condition in Mozambique and a Potentially Missed Diagnosis in Women Presenting with Eclampsia.
PMID: 31681909 [PubMed]
PMCID: PMC6824723
EC Microbiology
Molecular Detection of Leptospira spp. in Rodents Trapped in the Mozambique Island City, Nampula Province, Mozambique.
PMID: 31681910 [PubMed]
PMCID: PMC6824726
EC Neurology
Endoplasmic Reticulum-Mitochondrial Cross-Talk in Neurodegenerative and Eye Diseases.
PMID: 31528859 [PubMed]
PMCID: PMC6746603
EC Psychology and Psychiatry
Can Chronic Consumption of Caffeine by Increasing D2/D3 Receptors Offer Benefit to Carriers of the DRD2 A1 Allele in Cocaine Abuse?
PMID: 31276119 [PubMed]
PMCID: PMC6604646
EC Anaesthesia
Real Time Locating Systems and sustainability of Perioperative Efficiency of Anesthesiologists.
PMID: 31406965 [PubMed]
PMCID: PMC6690616
EC Pharmacology and Toxicology
A Pilot STEM Curriculum Designed to Teach High School Students Concepts in Biochemical Engineering and Pharmacology.
PMID: 31517314 [PubMed]
PMCID: PMC6741290
EC Pharmacology and Toxicology
Toxic Mechanisms Underlying Motor Activity Changes Induced by a Mixture of Lead, Arsenic and Manganese.
PMID: 31633124 [PubMed]
PMCID: PMC6800226
EC Neurology
Research Volunteers' Attitudes Toward Chronic Fatigue Syndrome and Myalgic Encephalomyelitis.
PMID: 29662969 [PubMed]
PMCID: PMC5898812
EC Pharmacology and Toxicology
Hyperbaric Oxygen Therapy for Alzheimer's Disease.
PMID: 30215058 [PubMed]
PMCID: PMC6133268
News and Events
May Issue Release
We always feel pleasure to share our updates with you all. Here, notifying you that we have successfully released the May issue of respective journals and the latest articles can be viewed on the current issue pages.
Submission Deadline for Upcoming Issue
ECronicon delightfully welcomes all the authors around the globe for effective collaboration with an article submission for the upcoming issue of respective journals. Submissions are accepted on/before May 25, 2022.
Certificate of Publication
ECronicon honors with a "Publication Certificate" to the corresponding author by including the names of co-authors as a token of appreciation for publishing the work with our respective journals.
Best Article of the Issue
Editors of respective journals will always be very much interested in electing one Best Article after each issue release. The authors of the selected article will be honored with a "Best Article of the Issue" certificate.
Certifying for Review
ECronicon certifies the Editors for their first review done towards the assigned article of the respective journals.
Latest Articles
The latest articles will be updated immediately on the articles in press page of the respective journals.