Research Article
Volume 9 Issue 3 - 2018
Early Results of Pediatric Crosslinking Therapy
Yusuf Avni Yilmaz1*, Ayse Demirciler Sonmez2 and Ece Turan-Vural1
1Ophthalmology Clinic, Haydarpasa Numune Training and Research Hospital, Istanbul, Turkey
2Ophthalmology Clinic, Faith Sultam Mehmet Training and Research Hospital, Istanbul, Turkey
*Corresponding Author: Yusuf Avni Yilmaz, Ophthalmology Clinic, Haydarpasa Numune Training and Research Hospital, Istanbul, Turkey.
Received: January 11, 2018; Published: February 24, 2018


Purpuse: To assess the the clinical results of collagen crosslinking in pediatric patients.

Methods: This prospective study included 17 eyes of 11patients uder 18 years old who had diagnosed progressive keratoconus. Uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA) using Snellen chart, corneal topography were evaluated. The corneal epithelium off method used and 0.1% Riboflavin mixed with 20% dextran solution applicated during 3 minute intervals for 30 minutes. Ultraviolet A irradiation with 18 mW/cm2 light power was administered for 5 minutes.

Results: All patients completed the 12-month follow-up. The increase in visual acuity at 6th and 12th month was statistically significant. No reduction in visual acuity and no worsening of K value was observed in any of the patients.

Conclusions: The results of this study indicate that riboflavin and ultraviolet-A induced corneal CXL is a promising therapeutic option for progressing keratoconus in pediatric population. 

Keywords: Corneal Collagen Cross-Linking; Keratoconus; Pediatric Keratoconus


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Citation: Yusuf Avni Yilmaz., et al. “Early Results of Pediatric Crosslinking Therapy”. EC Ophthalmology 9.3 (2018): 125-128.

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